OVERVIEW

Introduction to Clinical Microbiology, particularly to etiopathogenic and diagnostic significance, in the field of Human Medicine.

AIMS AND CONTENT

LEARNING OUTCOMES

Knowledge about different aspects of basic Microbiology to enable the graduate in Biotecnology to explore or expand any field connected to this topic.

AIMS AND LEARNING OUTCOMES

Knowledge of the fundamental and accessory bacterial structures. Knowledge of the pathways of bacterial damage to cells and the human body, pathways of toxic, inflammatory damage and elusion of immune surveillance. Knowledge of the structure and pathogenicity of human viruses. Knowledge of the basic structures of eukaryotic microorganisms, protozoa and yeasts and pathogenic mechanisms. Knowledge of the mechanisms of action of drugs with antibacterial, antiviral, antifungal and antiparasitic activity, and the related resistance mechanisms. Knowledge of the main lines of microbiological diagnostics. Knowledge of the existence, nomenclature and role of bacteria belonging to the normal human microbial population and of the existence, nomenclature and role of the most important bacteria, viruses, fungi, pathogenic parasites in human medicine.

Knowledge of fundamental differences between multicellular organisms and microorganisms, and between eukaryotic and prokaryotic cells, basic and ancillary structures of bacterial cells, genetic and peculiarities of bacterial cells, bacterial spores in general, and spore forming bacteria causing human disease. Knowledge of differences between saprophytic and parasite bacteria and the existence of exogenous and endogenous infections, the direct and indirect bacterial pathogenic mechanisms.

Knowledge of general, direct and indirect microbiological diagnostics, bacteriological diagnostics, antibacterial drugs, bacterial resistance to antibiotics, mechanisms of genetic onset and phenotype. Knowledge of major protozoa and yeasts. of medical interest and related diagnostic modes

Knowledge of structure of viruses in general and DNA and RNA viruses in particular, of replication and viral pathogenicity. Knowledge of viral diagnostics, direct and indirect. Knowledge of non-pathogenic parasitic bacteria, their nomenclature and localization in different districts of the human body. Knowledge of medical classification of pathogenic bacteria, viruses, protozoa and yeasts of medical interest.

Knowledge of the fundamental, accessory and peculiar bacterial structures as an extrinsic cause of general and, in particular, infectious diseases. Knowledge of the pathways of bacterial damage to cells and the human body, toxic, inflammatory and elusion of immune surveillance. Knowledge of the structure and pathogenicity of human viruses. Know the basic structures of eukaryotic microorganisms, protozoa and yeasts. Knowledge of antibacterial drugs and the main resistance mechanisms. Know the main lines of microbiological diagnostics, direct and indirect. To know the existence, nomenclature and role of bacteria belonging to the normal human microbial population and the existence, nomenclature and role of the most important bacteria, viruses, fungi, pathogenic parasites in human medicine.

TEACHING METHODS

Frontal lessons and laboratory.

SYLLABUS/CONTENT

Fundamental differences between multicellular organisms and microorganisms and between eukaryotic and prokaryotic cell

Structure of the bacterial cell

Genetics and metabolism peculiar to the bacterial cell

Bacterial spores

Saprophytic and parasitic bacteria. Exogenous and endogenous infections. The human microbiota

Bacterial pathogenic mechanisms

Essential principles of bacterial genetics

General microbiological and bacteriological diagnostics

Structure of viruses

Viral replication

Pathogenicity mechanisms of viruses and virological diagnostics.

Structure and classification of the main fungi of medical interest

Structure and classification of the main protozoa of medical interest

Mechanisms of action and resistance of drugs with antibacterial, antiviral, antifungal and antiparasitic activity.

RECOMMENDED READING/BIBLIOGRAPHY

Principi di Microbiologia Medica - La Placa - Soc. Ed. Esculapio \ Microbiologia Medica - Antonelli e Clementi - Casa Ed. Ambrosian

TEACHERS AND EXAM BOARD

Exam Board

MARIA CRISTINA MINGARI (President)

ROBERTA RICCIARELLI (President)

VINCENZO DI PILATO

LESSONS

Class schedule

The timetable for this course is available here: Portale EasyAcademy

EXAMS

EXAM DESCRIPTION

The exam takes place orally.

ASSESSMENT METHODS

The exam takes place in oral form, allowing to accurately assess the achievement of the expected learning outcomes

The evaluation parameters include:

• competence in the subject;
• ability to critically discuss the requested topics;
• the quality of the exposure and the correct use of the proper scientific terminology.

Failure to achieve the expected objectives requires the student to deepen the exam subject in a more suitable way.

Exam schedule