Knowledge of the mechanisms that control cellular and molecular level the proliferation differentiation and cell death.
Knowledge of the different stages of embryonic development of model organisms used in biotechnology research with particular attention to its control mechanisms.
Lectures and practical laboratory.
Any Student with documented Specific Learning Disorders (SLD), or with any special needs, should contact the Lecturer(s) and to the dedicated SLD Representative in the Department before class begins, in order to liaise and arrange the specific teaching methods so that the learning aims and outcomes may be met.
Cell cycle, cycle control system
S-phase, mitosis, cytokine, division control and cell growth
Hayflick limit. Cell growth factors and proliferation
Apoptosis, proteins that regulate apoptosis
Necrosis and autophagy
General aspects of cellular communication
Signaling via enzyme-linked receptors
Signaling via G-protein and intracellular mediators
Ion channels. Signal transduction and cellular response. Intracellular signaling pathways
Adhesion proteins, cell-cell adhesion
Basal plate, integrins and extracellular matrix
Cell-ECM interactions
Direct and indirect causes, microevolutionary process, tumour progression
Proto-oncogenes, oncogenes, anti-oncogenes
Oncogenesis from chemical, physical and viral agents
Molecular diagnosis and new therapeutic approaches
embryonic, foetal and adult, cancer stem cells
establishment of animal and/or human cell cultures
Preparation of culture media, thawing and freezing of cell lines or primary cultures. In vitro cell line expansion, cell count, viability test (MTT). Contamination of cell cultures. Cell biobanks.
Alberts B. et al. - Biologia Molecolare della cellula. Zanichelli.
Ricevimento: The students are able to book an appointment by phone, by mail or by aulaweb
Ricevimento: By appointment, upon contacting the Lecturer by e-mail: matteo.bozzo@unige.it
Ricevimento: By appointment by email: chiara.gentili@unige.it
Ricevimento: by appointment by email: sara.tavella@unige.it
Ricevimento: Prof. Sveva Bollini office hours for students are normally set by previous appointment requested by email. The office address is: Biology Section, Dept. Experimental Medicine; entrance: Via Pastore 3 or C.so Europa 30, second floor or Torre C3, c/o CBA, Cellular Oncology Lab, L. go R. Benzi 10, 16132 Genova. The lecturer's e-mail address and phone number are the following: sveva.bollini@unige.it; 0105558394. If necessary appointments may also take place on-line, depending on previous agreements between students and lecturer.
Ricevimento: Prof. Roberta Tasso: The office address is: Biology Section, Dept. Experimental Medicine; entrance: Via Pastore 3 or C.so Europa 30, second floor. The teacher's e-mail address is the following: roberta.tasso@unige.it. Alternatively, the teacher can be reached at the following phone number: 0105558394. If necessary, appointments may also take place on-line, depending on previous agreements between the students and the teacher.
SIMONA CANDIANI (President)
CHIARA GENTILI (President)
MATTEO BOZZO
I semester, October.
CELLULAR BIOLOGY AND DEVELOPMENT AND CELLULAR CULTURE AND DEVELOPMENT LABORATORY
Oral.
Oral examination.
