|SCIENTIFIC DISCIPLINARY SECTOR||CHIM/06|
This course continues and deepens the discussion of spectroscopic techniques (especially NMR, IR and MS) already discussed in the course of Organic Chemistry 2 of Bachelor Degree.
This course provides a more in-depth theoretical framework and further develops the range of practical applications aimed at determining the molecular structure of organic compounds, included the configurational and conformational aspects.
Particular emphasis is given to data analysis and the strategy for their interpretation, including the discussion about the practical solution of numerous real problems.
It is essential that the student has assimilated the notions taught in the course of Organic Chemistry 2, since only having aquired an adequate knowing of the fundamental aspects of this matter makes sense to deal with the study of the more advanced topics presented in this course.
6 ECTS of lectures (Descriptive slides are provided to students before classes through AulaWeb). Attendance is optional.
2 ECTS of classroom exercises and instrumental laboratory (the students are provided with slides about methods of approach to the solution of problems and with many problems, some addressed in classroom, others available for autonomous solution). Attendance is mandatory.
Several exercises requiring the identification of unknowns substances by means of the analysis of appropriate spectra with their interactive group discussion
Running NMR spectra of some organic molecules with different techniques and discuss them.
Application of the most common post-acquisition processing techniques of NMR spectroscopy.
• L. D. FIELD, S. STERNHELL, J. R. KALMAN, Organic Structures From Spectra (Wiley, 2013)
• P. CREWS, J. RODRIGUEZ, M. JASPARS, Organic Structure Analysis (Oxford University Press, 2010)
• J. B. LAMBERT, S. GRONERT, H. S. SHURVELL, D. A. LIGHTNER, R. G. COOKS, Organic Structural Spectroscopy (Prentice-Hall, 2010)
• D. H. WILLIAMS, I. FLEMING, Spectroscopic Methods in Organic Chemistry (McGraw-Hill, 2007)
• E. PRETSCH, P. BUHLMANN, M. BADERTSCHER, Structure Determination of Organic Compounds: Tables of Spectral Data (Springer, 2008)
• S. A. RICHARDS, J. C. HOLLERTON, Essential Practical NMR for Organic Chemistry (Wiley, 2011)
• J. KEELER, Understanding NMR Spectroscopy (Wiley, 2005)
• J. B. LAMBERT, E. P. MAZZOLA, Nuclear Magnetic Resonance Spectroscopy: An Introduction to Principles, Applications, and Experimental Methods (Prentice Hall College, 2003)
• R. S. MACOMBER, A Complete Introduction to Modern NMR Spectroscopy (Wiley, 1998)
Office hours: Every day from Tuesday to Friday from 11 to 13 and from 14.30 to 16.30, by appointment, in the study 915 of DCCI.
Written test (3 exercises of identification of unknown substances by means of the analysis of appropriate spectra)
Oral examination (3 main questions about the course topics, complemented by secondary questions arising from the student's discussion)
The written exam (for students of Chemical Sciences only) consists of 3 exercises of identification of organic compounds by analyzing their spectroscopic data.
The assessment takes into account the difficulty of the exercises, the identification accuracy, the degree of detail and accuracy of the considerations with which students comment on the allocation of spectroscopic data to unknown compounds. The written dissertation can be further analyzed and discussed with the student during the oral examination.
It is necessary to pass the written exam with sufficient assessment to be admitted to the oral test. The duration of the written examination results is one year: after this period the student is required to retake the written test to be admitted to the oral test.
The oral examination is conducted by the lecturer of the course and another competent teacher in the field, and has a duration of at least 45 minutes (usually about an hour). In this way, the commission is able to check the achievement of the lerning objectives of the course, with particular attention to the evaluation of the student's ability to relate in a profitable way the various lerned concepts and apply them to concrete cases of study. When the goals are not met (in the opinion of the Assesment Committee), the student is invited to deepen the study and to takeadvantage of further explanation by the lecturer, and then return to repeat the exam at a later date.