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GENERAL PATHOLOGY AND IMMUNOLOGY

CODE 67952
ACADEMIC YEAR 2022/2023
CREDITS
  • 2 cfu during the 2nd year of 9278 OSTETRICIA(L/SNT1) - GENOVA
  • SCIENTIFIC DISCIPLINARY SECTOR MED/04
    LANGUAGE Italian
    TEACHING LOCATION
  • GENOVA
  • SEMESTER 1° Semester
    MODULES This unit is a module of:
    TEACHING MATERIALS AULAWEB

    OVERVIEW

    The General Pathology and Immunology Science  are a multidisciplinary sciences relating  to human health: how and why it happens the health disturbance, it includes the molecular and cellular mechanisms that underlie the disease, ie etiopathogenesis and all aspects of the host defenses against infection.

    AIMS AND CONTENT

    AIMS AND LEARNING OUTCOMES

    The course aims to train experts in the field of midwifery. The course aims to provide a specific basis for basic materials needed for the student's education. The student will learn the fundamental skills necessary for the understanding of the biological basis and principal pathophisiology concepts of the General Pathology and Immunology presented during the course. 

    TEACHING METHODS

    The teaching activity is carried out through lectures with the aid of on-screen presentations. The teaching material is available in pdf version on Teams or aulaweb, to allow the student to learn and deepen the topics indicated in the course program and required for passing the final exam.

    In case of changes in the health and epidemiological situation, the lessons will be held at a distance (Teams).

    There are no student reception hours, but students can contact the teachers by email in order to make an appointment for further explanations.

     

    SYLLABUS/CONTENT

    IMMUNOLOGY

    Innate immunity: cells, molecules and mechanisms of the innate immune response, local and systemic inflammation, acute and chronic inflammation, variants of acute inflammation.

    Atherosclerosis and notes on cardiovascular diseases

    Adaptive immunity: maturation and functional characteristics of T and B lymphocytes. Antigen presentation and T-B interaction

    Immune system disorders: Allergy. Notes on immunodeficiencies, autoimmune and autoinflammatory diseases

    Passive immunity of the fetus / newborn: maternal-fetal interface, breastfeeding

    ONCOLOGY:

    benign and malignant tumors, metastases, local and systemic effects.

    Epidemiology (risk and prognostic factors).

    Molecular basis of tumor transformation: oncogenes, oncosuppressors and examples of neoplasms. Notes on epigenetic mechanisms (mRNA, methylation)

    Cancer stem cells (CSCs), tumor-associated angiogenesis and tumor microenvironment.

    Anti-tumor immune response, Natural Killer cells, escape mechanisms and tumor-associated inflammation

    HEMATOLOGY

    Hemopoiesis and hematopoietic stem cell transplantation

    Erythropoiesis, vitamins or iron deficiency anemia, maternal-fetal incompatibility

    RECOMMENDED READING/BIBLIOGRAPHY

    Didattic resources presented by teacher during the lessons

    For further information consult

    Abul K. Abbas et al.  Immunologia cellulare e molecolare, Edra

    Robbins e Cotran. Le basi patologiche delle malattie. Elsevier

    For further advice please contact the teacher.

    Students with SLD, disability or other special educational needs certification are strongly encouraged to contact the teachers at the beginning of the course to agree on teaching methods which, respecting the teaching objectives, take into account individual learning methods and provide suitable compensatory instruments.

     

    TEACHERS AND EXAM BOARD

    Exam Board

    VALERIO GAETANO VELLONE (President)

    FRANCESCA BUFFELLI

    SIMONE NEGRINI

    GABRIELLA PIATTI

    CRISTINA BOTTINO (President and Coordinator of Integrated Course)

    LESSONS

    LESSONS START

    2nd year, 1st semester

    Class schedule

    All class schedules are posted on the EasyAcademy portal.

    EXAMS

    EXAM DESCRIPTION

    The end-of-course exam aims to assess the achievement of the educational objectives of the course. The exams take place on the dates indicated in the calendar. Verification is oral, in person.

    The teacher verifies the achievement of the educational objectives by asking diversified questions relating to the programs actually carried out during the lesson hours. When the educational objectives have not been achieved, the student is invited to better verify his knowledge and to take the exam again in its entirety.

    In case of changes in the sanitary and epidemiological situation, the exams will be carried out remotely (TEAMS).

    Examination Committee: Prof. Cristina Bottino

    ASSESSMENT METHODS

    The assessment takes place only through the final exam which aims to ensure the effective acquisition by the student of the expected learning outcomes.

    In order to pass the exam (vote of not less than 18/30) the student must demonstrate that:

    - knows the principal topics

    - is able to reason by connecting the various topics

    - demonstrates ability to transverse and critically deal with the required arguments

    - Adopts of appropriate terminology.

    Students with SLD or other regularly certified special educational needs will be able to agree on written or oral modalities with the teacher, by contacting the teachers at least 10 days before the exam. They can also take advantage of 30% additional time.

    Exam schedule

    Date Time Location Type Notes
    12/01/2023 14:30 GENOVA Orale SEDE: Padiglione 1, fondi NB: per motivi di salute la Prof. Bottino non potrà essere presente. L'esame di patologia generale sarà scritto: 15 domande a risposta multipla (1 sola risposta esatta), due punti a domanda. Lode se si risponde a 16 domande
    12/01/2023 14:30 GENOVA Scritto SEDE: Padiglione 1, fondi NB: per motivi di salute la Prof. Bottino non potrà essere presente. L'esame di patologia generale sarà scritto: 15 domande a risposta multipla (1 sola risposta esatta), due punti a domanda. Lode se si risponde a 16 domande
    16/02/2023 14:30 GENOVA Orale SEDE: Padiglione 1, fondi
    15/06/2023 14:30 GENOVA Scritto SEDE: Padiglione 1, fondi ATTENZIONE: il prof. Vellone inizierà gli esami alle ore 13.30 L'esame della Prof. Piatti sarà scritto
    15/06/2023 14:30 GENOVA Orale SEDE: Padiglione 1, fondi ATTENZIONE: il prof. Vellone inizierà gli esami alle ore 13.30 L'esame della Prof. Piatti sarà scritto
    13/07/2023 14:30 GENOVA Orale Per un impegno inderogabile del prof. Vellone l'interrogazione di anatomia patologica si svolgerà il 13 luglio alle ore 9 presso l'anatomia patologia dell'Ospedale Gaslini (padiglione 2, terzo piano) Il resto dell'esame si svolgerà come previsto (13 luglio, ore 14.30, Padiglione 1 fondi, S. Martino)
    13/07/2023 14:30 GENOVA Scritto Per un impegno inderogabile del prof. Vellone l'interrogazione di anatomia patologica si svolgerà il 13 luglio alle ore 9 presso l'anatomia patologia dell'Ospedale Gaslini (padiglione 2, terzo piano) Il resto dell'esame si svolgerà come previsto (13 luglio, ore 14.30, Padiglione 1 fondi, S. Martino)
    14/09/2023 14:30 GENOVA Scritto SEDE: Padiglione 1, fondi La prova di Patologia generale-Immunologia sarà scritta
    14/09/2023 14:30 GENOVA Orale SEDE: Padiglione 1, fondi La prova di Patologia generale-Immunologia sarà scritta

    FURTHER INFORMATION

    Attendance allows the student to better learn the contents of the course because the teacher provides detailed explanations during the lessons and frames the topics with continuous references to the most current discoveries in the field of the subject. The teaching material is available online (Teams or Aulaweb)