OVERVIEW

The General Pathology and Immunology Science  are a multidisciplinary sciences relating  to human health: how and why it happens the health disturbance, it includes the molecular and cellular mechanisms that underlie the disease, ie etiopathogenesis and all aspects of the host defenses against infection.

AIMS AND CONTENT

AIMS AND LEARNING OUTCOMES

The course aims to train experts in the field of midwifery. The course aims to provide a specific basis for basic materials needed for the student's education. The student will learn the fundamental skills necessary for the understanding of the biological basis and principal pathophisiology concepts of the General Pathology and Immunology presented during the course. 

TEACHING METHODS

The teaching activity is carried out through lectures with the aid of on-screen presentations. The teaching material is available in pdf version on Teams or aulaweb, to allow the student to learn and deepen the topics indicated in the course program and required for passing the final exam.

In case of changes in the health and epidemiological situation, the lessons will be held at a distance (Teams).

There are no student reception hours, but students can contact the teachers by email in order to make an appointment for further explanations.

SYLLABUS/CONTENT

IMMUNOLOGY

Innate immunity: cells, molecules and mechanisms of the innate immune response, local and systemic inflammation, acute and chronic inflammation, variants of acute inflammation.

Atherosclerosis and notes on cardiovascular diseases

Adaptive immunity: maturation and functional characteristics of T and B lymphocytes. Antigen presentation and T-B interaction

Immune system disorders: Allergy. Notes on immunodeficiencies, autoimmune and autoinflammatory diseases

Passive immunity of the fetus / newborn: maternal-fetal interface, breastfeeding

ONCOLOGY:

benign and malignant tumors, metastases, local and systemic effects.

Epidemiology (risk and prognostic factors).

Molecular basis of tumor transformation: oncogenes, oncosuppressors and examples of neoplasms. Notes on epigenetic mechanisms (mRNA, methylation)

Cancer stem cells (CSCs), tumor-associated angiogenesis and tumor microenvironment.

Anti-tumor immune response, Natural Killer cells, escape mechanisms and tumor-associated inflammation

HEMATOLOGY

Hemopoiesis and hematopoietic stem cell transplantation

Erythropoiesis, vitamins or iron deficiency anemia, maternal-fetal incompatibility

RECOMMENDED READING/BIBLIOGRAPHY

Didattic resources presented by teacher during the lessons

For further information consult

Abul K. Abbas et al.  Immunologia cellulare e molecolare, Edra

Robbins e Cotran. Le basi patologiche delle malattie. Elsevier

For further advice please contact the teacher.

Students with SLD, disability or other special educational needs certification are strongly encouraged to contact the teachers at the beginning of the course to agree on teaching methods which, respecting the teaching objectives, take into account individual learning methods and provide suitable compensatory instruments.

TEACHERS AND EXAM BOARD

Exam Board

VALERIO GAETANO VELLONE (President)

FRANCESCA BUFFELLI

SIMONE NEGRINI

GABRIELLA PIATTI

CRISTINA BOTTINO (President and Coordinator of Integrated Course)

LESSONS

LESSONS START

2nd year, 1st semester

Class schedule

The timetable for this course is available here: Portale EasyAcademy

EXAMS

EXAM DESCRIPTION

The end-of-course exam aims to assess the achievement of the educational objectives of the course. The exams take place on the dates indicated in the calendar. Verification is oral, in person.

The teacher verifies the achievement of the educational objectives by asking diversified questions relating to the programs actually carried out during the lesson hours. When the educational objectives have not been achieved, the student is invited to better verify his knowledge and to take the exam again in its entirety.

In case of changes in the sanitary and epidemiological situation, the exams will be carried out remotely (TEAMS).

Examination Committee: Prof. Cristina Bottino

ASSESSMENT METHODS

The assessment takes place only through the final exam which aims to ensure the effective acquisition by the student of the expected learning outcomes.

In order to pass the exam (vote of not less than 18/30) the student must demonstrate that:

- knows the principal topics

- is able to reason by connecting the various topics

- demonstrates ability to transverse and critically deal with the required arguments

- Adopts of appropriate terminology.

Students with SLD or other regularly certified special educational needs will be able to agree on written or oral modalities with the teacher, by contacting the teachers at least 10 days before the exam. They can also take advantage of 30% additional time.

Exam schedule

FURTHER INFORMATION

Attendance allows the student to better learn the contents of the course because the teacher provides detailed explanations during the lessons and frames the topics with continuous references to the most current discoveries in the field of the subject. The teaching material is available online (Teams or Aulaweb)