LEARNING OUTCOMES

The course aims to provide the theoretical notions and practical skills related to the main techniques of qualitative analysis of pharmaceutical interest substances. The course includes practical laboratory exercises.

AIMS AND LEARNING OUTCOMES

The aim of the course is to provide the theoretical knowledge and the technical skills on the most relevant methods used for the qualitative analysis of a pharmaceutically relevant compound. At the end of the course, the student will be familiar with the different tests used for the chemical identification of the compounds and will be able to critically analyze the experimental results.

PREREQUISITES

Organic and inorganic chemistry

TEACHING METHODS

Lessons and laboratory exercises.

SYLLABUS/CONTENT

Qualitative analysis of inorganic salts: systematic search of anions: phosphates, thiosulphates, iodides, bromides, chlorides, sulphates, nitrates and cations: silver, barium, bismuth, copper, alluminium, iron, manganese, zinc, calcium, magnesium

Qualitative analysis of organic compounds: preliminary assays and test for specific functional groups: alcohols, polyalcohols, carbohydrates, phenols, carboxylic acids, esters, amines, amides, aminoacids, sulfonamides, pyridine and purine derivatives)

Spectroscopic methods: notions about UV/VIS, IR, NMR, mass spectrometry

RECOMMENDED READING/BIBLIOGRAPHY

F. Savelli, O. Bruno, “Analisi Chimico Farmaceutica”, Ed. Piccin

A. Carta, M. G. Mamolo, F. Novelli, S. Piras, “Analisi Farmaceutica Qualitativa”, Ed. EdiSES

G. Caliendo, A. Carocci, A. Carta, A. Catalano, A. Corvino, F. Fiorino, F. Frecentese , E. Magli, M.G. Mamolo, E. Perissutti , S. Piras, I. Saccone, V. Santagada, L. Scipione, B. Severino, D. Zampieri, "Manuale di analisi qualitativa", Ed. EdiSES