AIMS AND LEARNING OUTCOMES

The following are the principal aims of General Pathology teaching:

• The knowledge of the aetiology and pathogenesis of human diseases;
• The understanding of the molecular mechanisms responsible for cell damage, tumor growth and inflammation.

At the end of the course, the student will be able to:

• Be fully knowledge able of the aetio-pathogenesis of the principal human diseases;
• Classify the different origins of diseases;
• Clearly identify the mechanisms of cell adaptation to damage and cell death-dependent changes;
• Explain the inflammation process and tissue repair;
• Understand the principal molecular and morphological aspects of tumor cells.

PREREQUISITES

Basic knowledge in anatomy, histology, biochemistry, physiology

TEACHING METHODS

T

The teaching is composed of 20 hours of live lectures on all the syllabus subjects which are illustrated through specific Power Point presentations available on Aulaweb. The frontal lessons could be carried out remotely in online mode using the Teams platform  if it will be necessary.

The tutors suggest the use of reference books to further develop the various topics in order to be fully prepared for the exam.

Note that, in line with university regulations, the attendance to these lectures is compulsory.

SYLLABUS/CONTENT

Causes of disease: injury by physical agents (radiations, thermal and traumatic  injury); chemical and drug injury.

Cellular pathology: cell injury and cellular adaptations. Regressive processes ; Atrophy, Degenerative processes and cell death (apoptosis and necrosis)

Acute and chronic inflammation: Inflammatory cells, Chemical mediators of inflammation, Inflammatory cytokines, Leucocyte migration, Systemic effects of inflammation, Acute phase response, Classification of acute inflammation, Chronic inflammation, Granulomas

RECOMMENDED READING/BIBLIOGRAPHY

Patologia generale: 1) GM Pontieri, Patologia generale, Piccin, 2) M. Parola, Patologia Generale, EdiSes.