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BIOLOGY II (CYTOLOGY, HISTOLOGY) AND LABORATORY COURSE

CODE 101966
ACADEMIC YEAR 2022/2023
CREDITS
  • 10 cfu during the 1st year of 8756 BIOTECNOLOGIE (L-2) - GENOVA
  • SCIENTIFIC DISCIPLINARY SECTOR BIO/17
    LANGUAGE Italian
    TEACHING LOCATION
  • GENOVA
  • SEMESTER 2° Semester
    PREREQUISITES
    Prerequisites
    You can take the exam for this unit if you passed the following exam(s):
    • Biotechnology 8756 (coorte 2022/2023)
    • BIOLOGY AND GENETICS 80754
    Prerequisites (for future units)
    This unit is a prerequisite for:
    • Biotechnology 8756 (coorte 2022/2023)
    • CELLULAR BIOLOGY AND DEVELOPMENT AND CELLULAR CULTURE AND DEVELOPMENT LABORATORY 66910
    • MICROBIOLOGY, GENERAL PATHOLOGY AND IMMUNOLOGY AND LABORATORY 66902
    TEACHING MATERIALS AULAWEB

    OVERVIEW

    The course titled "Biology II" aims to integrate the knowledge of "functional histology" and cell biology by aiming to provide students with knowledge about the organization and function of cells and human tissues with particular attention to the connection between morphology and function.

    AIMS AND CONTENT

    LEARNING OUTCOMES

    Know structure, organization and function of different human tissues and morphological-functional characteristics of cells that compose them.

    AIMS AND LEARNING OUTCOMES

    The purpose of the course is to provide the student with a complete view of the morphological and functional organization of tissues, with particular attention to the cells that compose them.

    To this aim, basic and advanced methods for analyzing the organization of human tissues and how this organization is instrumental in ensuring full homeostatic tissue function are discussed.

    The course thus aims at:

    1. provide basic concepts on morphology, cellular and molecular organization of human tissues;

    2. discuss in depth the cellular and molecular characteristics of the different stem cell populations in the various tissues;

    3. describe the functional properties of the various tissues and cells that compose them, focusing on physiopathological aspects as well;

    4. observe and appropriately describe a histological structure in optical microscopy.

    During the last lessons of the course, students are given some knowledge assessment tests to which students respond individually and anonymously. Immediately after each test, feedback is provided by the teacher, who immediately shows the correct answers. A moment of discussion of the topics that emerged in the tests follows, with the possibility for the teacher to clarify any doubts.

     

    The expected learning outcomes are:
    1. Knowledge and understanding.
    a. Knowledge of the terminology of the discipline
    b. Knowledge of investigation methods in cytology and histology
    c. Knowledge of the subcellular, cellular and tissue structures of the human body
    d. Knowledge of the mechanisms through which the organization of the different structures of the human body is achieved
    e. Understanding of the morpho-functional characteristics of the microscopic and ultrastructural organization of human cells and supracellular units, represented by tissues, multi-tissue units and morphofunctional units.

    2. Ability to apply knowledge and understanding.
    a. Knowing how to recognize and describe in an appropriate way a histological structure in optical microscopy, starting from its cellular organization.
    b. Integrate knowledge relating to the mechanisms of cell differentiation, interactions between cells and histogenesis with related functional and clinical aspects.

    3. Transversal skills.
    The acquired knowledge is essential cultural background for a full understanding of the anatomy, physiology and pathophysiology of the organs and systems of the human body

    PREREQUISITES

    General knowledge of chemistry, biology and genetics

    TEACHING METHODS

    Class teaching and practical exercises for the recognition of histological preparations

    It is possible that the method of conducting the lessons is changed due to emergency situations that prevent the performance of the lessons in attendance. In this case the lessons will be carried out through the Teams platform using suitable replacement teaching tools. For the practical part, high resolution slide images and / or virtual microscope will be used.

    SYLLABUS/CONTENT

    EUKARYOTIC CELL:

    The main steps in eukaryotic cell evolution

    The plasma membrane:

    Structure and functions

    Membrane transports

    Endocytosis and esocytosis

    The cytoplasm:

    Hyaloplasm

    Ribosomes

    Rough-surfaced endoplasmic reticulum (RER)

    Smooth-surfaced endoplasmic reticulum (REL)

    Golgi apparatus

    Lysosomes

    Peroxisomes

    Mitochondria

    The cytoskeleton

    Cell movement

    Cell motility and intracellular transport

    Cell junctional comlexes

    The nucleous

    The nucleolus

    Cell cycle and mitosis

     

    TISSUES:

    Epithelial tissue:

    Main characteristics of epithelia

    Lining epithelia: organization and classification

    Structural surface differentiations of epithelial cells (microvilli, stereocilia, cilia)

    Secretory epithelia:

    •          exocrine glands

    •          endocrine glands

     

    Connective tissue:

    Extracellular matrix:

    •          fibers

    •          ground substance

    Cell components of connective tissue

    Connective tissue proper

    Support connective tissue: cartilage and bone tissue

    Ossification

    Trophic connective tissue: blood and lymph

    Lymphatic tissue

    Cells of the innate and adaptive immune system

    Muscle tissue:

    • striated skeletal and cardiac muscle
    • smooth muscle tissue

    Myofibril structure and muscle  contraction

    Nerve tissue:

    • neurons
    • glial cells
    • nerve fibers
    • synapses and impulse transmission

    RECOMMENDED READING/BIBLIOGRAPHY

    Istologia di Monesi 7° edizione Casa Editrice Piccin

    Citologia, Istologia e Anatomia Microscopica a cura di D. Zaccheo e M. Pestarino Casa Editrice Pearson

    Atlante on-line (accesso libero): http://www.istologia.unige.it/

    Istologia (testo e atlante) di M.H. Ross e W. Pawlina Casa Editrice Ambrosiana

    TEACHERS AND EXAM BOARD

    Exam Board

    ROBERTA CASTRICONI (President)

    EMANUELA MARCENARO (President)

    MARIELLA DELLA CHIESA

    ALESSANDRA DONDERO

    SILVIA PESCE

    LESSONS

    LESSONS START

    March 2023

    Class schedule

    All class schedules are posted on the EasyAcademy portal.

    EXAMS

    EXAM DESCRIPTION

    Practical test and oral examination

     

    In this case, the methods of conducting the exam may be subject to changes with the possible inclusion of a written test. The Teams platform and / or the aulaweb portal will be used.

    ASSESSMENT METHODS

    The examamination includes two tests.

    The first consists of a practical test where the student must describe two histological preparations by the use of optical microscope.

    The second test, performing only upon the positive evaluation of the first test, consists of an oral examination that is subordinated to passing the practical test and which includes cytology questions and histology questions concerning the teaching content.

     

    In this case, the methods of conducting the exam may be subject to changes with the possible inclusion of a written test. The Teams platform and / or the aulaweb portal will be used.

    Exam schedule

    Date Time Location Type Notes
    16/01/2023 09:30 GENOVA Scritto Gli esami saranno ORALI e si svolgeranno presso l'AULA MUSEO, piano terra dell'istituto di Anatomia Umana, Via De Toni 14, Genova.
    16/01/2023 09:30 GENOVA Orale Gli esami saranno ORALI e si svolgeranno presso l'AULA MUSEO, piano terra dell'istituto di Anatomia Umana, Via De Toni 14, Genova.
    07/02/2023 09:30 GENOVA Scritto Gli esami saranno ORALI e si svolgeranno presso l'AULA MUSEO, piano terra dell'istituto di Anatomia Umana, Via De Toni 14, Genova.
    07/02/2023 09:30 GENOVA Orale Gli esami saranno ORALI e si svolgeranno presso l'AULA MUSEO, piano terra dell'istituto di Anatomia Umana, Via De Toni 14, Genova.
    21/06/2023 09:30 GENOVA Orale Gli esami saranno ORALI e si svolgeranno presso l'AULA MUSEO, piano terra dell'istituto di Anatomia Umana, Via De Toni 14, Genova.
    21/06/2023 09:30 GENOVA Scritto Gli esami saranno ORALI e si svolgeranno presso l'AULA MUSEO, piano terra dell'istituto di Anatomia Umana, Via De Toni 14, Genova.
    10/07/2023 09:30 GENOVA Scritto Gli esami saranno ORALI e si svolgeranno presso l'AULA MUSEO, piano terra dell'istituto di Anatomia Umana, Via De Toni 14, Genova.
    10/07/2023 09:30 GENOVA Orale Gli esami saranno ORALI e si svolgeranno presso l'AULA MUSEO, piano terra dell'istituto di Anatomia Umana, Via De Toni 14, Genova.
    19/09/2023 09:30 GENOVA Scritto Gli esami saranno ORALI e si svolgeranno presso l'AULA MUSEO, piano terra dell'istituto di Anatomia Umana, Via De Toni 14, Genova.
    19/09/2023 09:30 GENOVA Orale Gli esami saranno ORALI e si svolgeranno presso l'AULA MUSEO, piano terra dell'istituto di Anatomia Umana, Via De Toni 14, Genova.