Salta al contenuto principale della pagina

ANIMAL BIOLOGY

CODE 55417
ACADEMIC YEAR 2022/2023
CREDITS
  • 6 cfu during the 1st year of 8452 FARMACIA (LM-13) - GENOVA
  • SCIENTIFIC DISCIPLINARY SECTOR BIO/13
    TEACHING LOCATION
  • GENOVA
  • SEMESTER 1° Semester
    PREREQUISITES
    Prerequisites (for future units)
    This unit is a prerequisite for:
    • Pharmacy 8452 (coorte 2022/2023)
    • GENERAL PHARMACOLOGY AND TOXICOLOGY 80324
    • PHARMACOGNOSY AND PHARMACOVIGILANCE 80328
    • GENERAL PHYSIOLOGY (PHAR)(MD) 60808
    • IMMUNOLOGY 64184
    • GENERAL PATHOLOGY 64187
    • PHARMACOLOGY AND PHARMACOTERAPY 80327
    TEACHING MATERIALS AULAWEB

    OVERVIEW

    This course introduces the student to the cell main functions and mechanisms. The fundamental notions of cell biology -from the inner cell organization up to the handling of the genetic information- will be discussed in order to present the cell as the living functional autonomous unit and to evidence its properties that are useful and mandatory to generate tissues and organs.

    AIMS AND CONTENT

    LEARNING OUTCOMES

    The students will learn how fundamental molecular mechanisms regulate the main cellular functions, starting with morphology and internal organization of the cell to end up with the processing of the genetic information and the generation of specialized cell types. The main aim is to clearly define the cell as an autonomous functional living unit as well as a component of a higher-grade hierarchical order in living tissues and organs.

    AIMS AND LEARNING OUTCOMES

    At the end of the course the student must retain: a) knowledge of the morphology of prokaryotic and eukaryotic cells; b) knowledge of the internal organelles of the cells, of their structure and functions, including the  molecular details; c) comprehension of the controls ruling cellular communications and signaling, gene expression and cell contacts; d) comprehension of DNA replication, and genetic inheritance, including the laws that rule those processes; e) knowledge of the cell cycle, both mitotic and meiotic. The student must be able to compare and explain (why and how) different cellular mechanisms, cell organs or cell types respond to specific stimuli. Students are also required to use the appropriate scientific terminology. We expect that students will be able to understand a deeper study of cell homeostasis and metabolism in the subsequent courses and that they will be able to consider the cell as a functional unit, suitable for therapeutic and pharmacological treatment.

    TEACHING METHODS

    The course lasts 48 hours of front lessons, provided either in presence or on-line –through the informatics software platforms available in the University- during which lesson items are presented through PowerPoint presentations; critical discussion and observations during lessons are encouraged. In some lessons interactive teaching, by means of freely available web resources, will also be performed. Textual and non-textual material is available for the students on the AulaWeb site, through controlled access, as well as a simulation of the written text to trial students’ competence and learning.

    SYLLABUS/CONTENT

    The course is essentially divided in six main themes. The first is dedicated to the Biological Macromolecules and it will present the essential characteristics of the most relevant biological molecules (water, lipids, carbohydrates and proteins) and of their chemical bonds, to elucidate their functions and to provide a proper basic knowledge for the comprehension of the remaining parts of the course. The second part –Cytology- will deal with the morphological organization of the prokaryotic and eukaryotic cells. Detailed anatomy and functions will be examined for the cell membrane (different membrane models, lipid composition, endo- and exocytosis functions, secretion pathways) and for the cell organelles (Golgi apparatus, smooth and rough endoplasmic reticulum, lysosomes, peroxisomes, mitochondria, nucleus, including chromatin structure and cytoskeletal organization). The third part – Cell interactions- will deal with cellular communications, including extracellular matrix proteins and their homophylic or heterophylic interactions. The entire fourth part is totally dedicated to Genomic Information and Expression (structure and characteristics of DNA and RNA, transcription, translation, regulation of gene expression, post-translational modifications of the proteins). The fifth subject is Cell Proliferation; cell cycle mechanisms and their regulations will be considered; apoptosis, cell transformation, mitosis, meiosis and a detailed description of gametogenesis will be subjects of regular lessons. Brief and general descriptions of embryo development and cell differentiation pathways, as well as their relevant control mechanisms, will also be presented. The last theme will deal with Genetics, introducing the biological effects and meaning of point, chromosomal and genomic mutations; Mendelian inheritance and laws will be presented, as well as heterochromosome-linked genetic diseases.

    RECOMMENDED READING/BIBLIOGRAPHY

    The following list comprises the suggested textbook(s) for the course: 

    Alberts et al. “L’essenziale di biologia molecolare della cellula”, Ed. Zanichelli

    Becker et al.: “Il mondo della cellula”, Ed. Pearson

    Karp et al.: “Biologia cellulare e molecolare”, Ed. EdiSES

    Ginelli et al.: "Molecole, cellule e organismi", Ed. EdiSES

    TEACHERS AND EXAM BOARD

    Exam Board

    PAOLO GIANNONI (President)

    RODOLFO QUARTO

    PAOLO GIORDANI (Substitute)

    LESSONS

    LESSONS START

    Location, date and timetable of the lessons will be provided by the competent office.

    Class schedule

    All class schedules are posted on the EasyAcademy portal.

    EXAMS

    EXAM DESCRIPTION

    The exam consists of a written test and of an oral part. The test, either written or provided on-line through the Esami.Aulaweb platform, includes 15 multiple-choice questions (and/or graphical, and/or correlation); each question has a value of 2 (two) points, for a total amount of 30 (thirty available points); the test is to be answered in a total of 15 minutes. Questions deal with any of the subjects presented and discussed during the regular lessons. To pass the test, students are required to answer correctly to at least 9 answers (i.e. 9 correct answers for a total of at least 18 points). Passing the written test is mandatory to gain access to the oral examination.

    ASSESSMENT METHODS

    During the ongoing lessons students will face tests, based on a game-to-learn approach, on specific parts of the program. The aim of these tests is to evidence possible scarce knowledge/comprehension of such portions   and to render the students familiar with the types of questions of the written final examination; however scores will not contribute to the final evaluation.

    In the formal exam session the student will have to pass the written part to evidence a retained overall knowledge of the subjects. Each test will include questions relating all the main items of the course. Passing the written test allows access to the oral examination, during which the student will be asked to answer several questions, of graded difficulty and complexity, to evaluate his/her specific competence on the subjects, language and terminology, and correlation capacities. Students are also encouraged to fill-in a self-evaluation module (not mandatory) before and after the written test, and subsequently encouraged to confront their putative results with the real score, in order to stimulate a correct perception of the level of competence in the subject.

    Exam schedule

    Date Time Location Type Notes
    07/04/2023 09:00 GENOVA Scritto + Orale Gli studenti devono verificare orari, modalità e indicazioni di sede per la fruizione dell'esame sulle apposite pagine di Esami2.Aulaweb dedicate.
    20/06/2023 09:00 GENOVA Scritto + Orale Gli studenti devono verificare orari, modalità e indicazioni di sede per la fruizione dell'esame sulle apposite pagine di Esami2.Aulaweb dedicate.
    07/07/2023 09:00 GENOVA Scritto + Orale Gli studenti devono verificare orari, modalità e indicazioni di sede per la fruizione dell'esame sulle apposite pagine di Esami2.Aulaweb dedicate.
    24/07/2023 09:00 GENOVA Scritto + Orale Gli studenti devono verificare orari, modalità e indicazioni di sede per la fruizione dell'esame sulle apposite pagine di Esami2.Aulaweb dedicate.
    08/09/2023 09:00 GENOVA Scritto + Orale Gli studenti devono verificare orari, modalità e indicazioni di sede per la fruizione dell'esame sulle apposite pagine di Esami2.Aulaweb dedicate.
    26/01/2024 09:00 GENOVA Scritto + Orale Gli studenti devono verificare orari, modalità e indicazioni di sede per la fruizione dell'esame sulle apposite pagine di Esami2.Aulaweb dedicate.
    15/02/2024 09:00 GENOVA Scritto + Orale Gli studenti devono verificare orari, modalità e indicazioni di sede per la fruizione dell'esame sulle apposite pagine di Esami2.Aulaweb dedicate.

    FURTHER INFORMATION

    Tutor-driven training sessions are also encouraged, particularly for students that have attempted and failed the exam several times. Informations relative to the tutoring sessions are normally provided during the initial lessons, but additional infos can be provided also via the AulaWeb post system. The Teacher is also available to trial students with training written tests before exam sessions, upon request.