CODE 106959 ACADEMIC YEAR 2022/2023 CREDITS 5 cfu anno 2 INGEGNERIA CHIMICA E DI PROCESSO 10376 (LM-22) - GENOVA SCIENTIFIC DISCIPLINARY SECTOR ING-IND/34 TEACHING LOCATION GENOVA SEMESTER 1° Semester TEACHING MATERIALS AULAWEB OVERVIEW The course introduces to the student the main plants and processes for the production, characterization, and engineering of innovative tools for biomedical applications, such as biomaterials, nanoparticles, and biosensors, to their structural and applicative properties, to their interaction mechanisms with tissues or with biological samples. AIMS AND CONTENT LEARNING OUTCOMES The main purpose of the theoretical part of the teaching is to provide students with basic knowledge related to biomolecules, cell biology and biochemistry and biomaterials. The laboratory part aims to make the student acquire basic knowledge on biomaterial processing techniques and on their characterization. AIMS AND LEARNING OUTCOMES The course aims to describe in detail, after an introduction to biomolecules and cell physiology, the plants and processes for the production and characterization of biomaterials, nanosystems, and biosensors. Attendance and participation to the activities (classes and laboratory activities) and individual study will allow the student to: 1) have an in-depth knowledge of the main classes of natural or synthetic molecules of interest for bioengineering applications; 2) know the structural and functional organization at cellular and tissue level; 3) have knowledge of biomaterials, nanosystems, and biosensors manufacturing plants; 4) have knowledge on the manufacturing processes of biomaterials, nanosystems, and biosensors; 5) have knowledge on the characterization activities on biomaterials, nanosystems, and biosensors; 6) have basic knowledge on bioreactors used in bioengineering; 7) have acquired the technical language of bioengineering to communicate clearly and effectively with specialist interlocutors; 8) have developed a capacity for understanding and solving bioengineering problems; 9) have developed an ability to learn the subject that allows the student to independently investigate the main issues, considering the essential need for continuous updating that the discipline requires. PREREQUISITES Students should have basic notions of inorganic chemistry, organic chemistry, and material science technology. TEACHING METHODS The course consists of 20 classes that are held in the classroom by using presentations, for a total of 40 hours (4 CFU). Part of the course includes three laboratory activities in which students can actively participate, for a total of 10 hours (1 CFU). At the end of the class of the module on biomaterials, nanosystems, and biosensors the related laboratory activity will be done. The dates of the laboratory activities will be communicated by the teacher at the beginning of the course. Attendance to classes and laboratory activities is recommended. SYLLABUS/CONTENT The course will deal with the following topics: natural molecules (complex polysaccharides, protein structures, complex lipids, and nucleic acids) and synthetic molecules (polymers) that find application in bioengineering; the structure and function of the main cellular components; the complexity of the structural and functional organization of biological tissues; an overview on biosignaling; plants for the production of biomaterials, nanosystems, and biosensors; processes for the production of biomaterials, nanosystems, and biosensors; techniques for the characterization of biomaterials, nanosystems, and biosensors; bioreactors for biomedical applications. As part of the course, there are three laboratory experiences that will concern the production of biomaterials through the electrospinning and 3D printing technique, the production and characterization of nanosystems (nanoliposomes and polymeric nanoparticles), and the production and validation of biosensors. RECOMMENDED READING/BIBLIOGRAPHY The material presented during classes will be provided to students through AulaWeb and this will be sufficient for preparing and passing the exam. The text books, listed below, can be a good support for the preparation of the exam: "Introduction to Bioengineering", Y.C. Fung; "Biomaterials and Bionanotechnology", R.K. Tekade; "Nanostructures and Nanomaterials: Synthesis, properties and applications", G. Cao and Y. Wang. TEACHERS AND EXAM BOARD PIER FRANCESCO FERRARI Ricevimento: The teacher receives by appointment, fixed by e-mail (pier.francesco.ferrari@unige.it), at his office in via Opera Pia, 15, pavilion A, first floor. Exam Board PIER FRANCESCO FERRARI (President) LAURA PASTORINO (President) ROBERTO RAITERI LESSONS LESSONS START https://corsi.unige.it/10376/p/studenti-orario Class schedule The timetable for this course is available here: Portale EasyAcademy EXAMS EXAM DESCRIPTION The final exam consists of an oral exam which includes a series of questions that may be related to the entire program showed during classes and laboratory activities. ASSESSMENT METHODS The preparation of the students is validated by passing the exam. Student ability to critically discuss the most important plants and processes in the bioengineering sector will be evaluated. The assessment will include, in addition to the contents, also the language properties and the ability of critical discussion, thus demonstrating not only mnemonic learning but a more mature assimilation of the different topics. Exam schedule Data appello Orario Luogo Degree type Note 10/01/2023 09:00 GENOVA Orale 24/01/2023 09:00 GENOVA Orale 10/02/2023 09:00 GENOVA Orale 14/06/2023 09:00 GENOVA Orale 03/07/2023 09:00 GENOVA Orale 21/07/2023 09:00 GENOVA Orale 05/09/2023 09:00 GENOVA Orale FURTHER INFORMATION Working students and students affected by SLD, disability, or other special educational needs are advised to contact the teacher at the beginning of the course to discuss on teaching and examination methods that, in compliance with the teaching objectives, take into account individual learning modalities. OpenBadge PRO3 - Soft skills - Personale avanzato 1 - A PRO3 - Soft skills - Alfabetica avanzato 1 - A