OVERVIEW

Integrate course Blood Disease

The course of Immunohematology II provides students with theoretical and practical knowledge in the field of Immuno-hematology. Starting from the basic notions on blood cells and antibodies, this course leads students through techniques and methodologies applied to transfusion medicine and for the study of immunopathology. In particular, it provides information concerning both the technical aspects and the clinical relevance of these tests.

AIMS AND CONTENT

LEARNING OUTCOMES

The general objectives of the course of Immunohematology II consist in providing students with the theoretical and practical knowledge relative to the analyses applied to transfusion medicine and to the study of immunopathology.

AIMS AND LEARNING OUTCOMES

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Knowledge of immune system physiology; knowledge of the main techniques for the study of the immune system and immunopathology including:

Cell Phenotyping

Analysis of T cell proliferation, cytokine secretion, cytotoxicity

Immunoenzymatic assays

ANA and ENA

Tests for diagnosis of immunodeficiencies

PREREQUISITES

Basic notions of Hematology and Immunology

TEACHING METHODS

Teaching will be provided by frontal lessons. During these lessons the students will have the opportunity to learn the arguments concerning the objects of the course and to interact with the professors in order to clarify unclear issues.

SYLLABUS/CONTENT

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 Criobiology.The profession and role of tslb in immunohematology.Quality controls

Innate immunity; adoptive immunity; techniques for phenotypic characterization of immune cells; techniques for the study of lymphocyte proliferation activity; techniques for the study of cytotoxicity;

techniques for the study of cytokine secretion; techniques for the study of antigen specificity through MHC pentamers; ANA; ENA

RECOMMENDED READING/BIBLIOGRAPHY

Blood Transfusion 40th National Conference of Transfusion Medicine Studies (Rimini, 23-26 May 2012)

Title: Extended red blood cell typing of periodic donors at the SIT of the E.O. Galliera Hospital in Genoa: experience on the first thousand donors.

SIMTI:Italian Society of Trasfusion and Immunohematology Medicine.

SISTRA/CNS :National Center Blood.Handbook of the various instrument.National Lines Guides

Abul Abbas: Cellular and Molecular immunology, eight edition

TEACHERS AND EXAM BOARD

Exam Board

GILBERTO FILACI (President)

SILVIA NASO (President)

ORELLA AGOSTA

ROBERTO MASSIMO LEMOLI

GIANLUCA UBEZIO

MAURIZIO MIGLINO (President and Coordinator of Integrated Course)

LESSONS

LESSONS START

October 2023

Class schedule

IMMUNOHEMATOLOGIC TECHNIQUES 2

EXAMS

EXAM DESCRIPTION

The learning by the students will be examined by oral examination performed answering questions relative to the educational objectives of the course.

ASSESSMENT METHODS

Assessment of learning by the students will be performed asking, during the lessons and at the momento of final examination, questions relative to the following educational objectives:

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Knowledge of immune system physiology; knowledge of the main techniques for the study of the immune system; knowledge on Translational Medicine.

Exam schedule