CODE 112668 ACADEMIC YEAR 2023/2024 CREDITS 6 cfu anno 3 INGEGNERIA BIOMEDICA 8713 (L-8) - GENOVA SCIENTIFIC DISCIPLINARY SECTOR ING-INF/06 LANGUAGE Italian TEACHING LOCATION GENOVA SEMESTER 2° Semester TEACHING MATERIALS AULAWEB OVERVIEW The course provides an overview of in vitro and in vivo neuroengineering aimed at providing the theoretical and methodological skills related to the study of the interaction of physical devices with the human brain at various levels of complexity, from the level of single cells and small neural networks, up to the entire nervous system and its interactions with the environment. AIMS AND CONTENT AIMS AND LEARNING OUTCOMES At the end of the course, the student: Will have the basis on in vitro and in vivo neuroengineering both in research and in clinical practice. Will have the basis that will allow designing and performing experiments with nervous cells to characterize both morphological (microscopy) and electrophysiological (multi-electrode recordings) properties, recognizing strengths and weaknesses of the different experimental models. Will have the basis that will allow identifying the critical issues that people with neuromotor problems face daily and propose technological solutions to improve their condition. Will be able to analyze and present experimental results appropriately. PREREQUISITES There are no formal prerequisites, but the course requires basic knowledge of physiology, informatics and bioelectronics. TEACHING METHODS Frontal lessons Seminars by industry experts (clinicians and engineers working in the field of neuroengineering) Practical exercises, presentations SYLLABUS/CONTENT Introduction to neural interfaces (brain- and body-machine interfaces). Introduction to the complexity of the brain both from a structural and functional point of view. In vitro models to study large-scale networks of nervous cells (e.g., slices, cell cultures, spheroids, organoids, etc.). Morphological and electrophysiological characterization of in vitro neuronal populations and their engineering. Consequences and problems related to damage or disease affecting the central or peripheral nervous system. Existing technological solutions to replace or recover motion lost due to damage to the nervous system. TEACHERS AND EXAM BOARD CAMILLA PIERELLA Ricevimento: For appointment contact: camilla.pierella@unige.it MARTINA BROFIGA Ricevimento: For appointment contact: martina.brofiga@unige.it Exam Board CAMILLA PIERELLA (President) SERENA RICCI MARTINA BROFIGA (President Substitute) LESSONS Class schedule The timetable for this course is available here: Portale EasyAcademy EXAMS EXAM DESCRIPTION Discussion of the report containing the used techniques and the results achieved by the exercitations. Exam schedule Data appello Orario Luogo Degree type Note 31/05/2024 09:30 GENOVA Orale 21/06/2024 09:30 GENOVA Orale 19/07/2024 09:30 GENOVA Orale 13/09/2024 09:30 GENOVA Orale