OVERVIEW

Medicine is evolving rapidly into a genomic medicine discipline after successful sequencing of human genomes. As a result, traditional diagnostics, therapeutics and prognostics in patients will soon become outdated.

Recent advances in genomics have led to the identification of new genes responsible for hereditary and inflammatory diseases, generating a huge impact in our understanding the genetic basis of structural and functional defects and pathological mechanisms underlying ophthalmological diseases.

AIMS AND CONTENT

AIMS AND LEARNING OUTCOMES

The course provides students with theoretical and practical knowledge of the molecular mechanisms responsible for hereditary pathologies in ophthalmology and on biomolecular techniques for their diagnosis and desirable treatment.

TEACHING METHODS

The teaching includes 8 hours of lectures.

N.B.: Students with valid certifications for Specific Learning Disorders (SLDs), disabilities or other educational needs are invited to contact the lecturer and the School/Department's disability referent at the beginning of the course to agree on possible teaching modalities that, while respecting the teaching objectives, take into account individual learning patterns.

SYLLABUS/CONTENT

Cellular structure and  physiology

DNA structure and biochemical characteristics

The human genome

Genes and variants

Genetic alterations and mutations

Molecular biology techniques applied to the diagnosis and treatment of genetic diseases

Gene Therapy: most common vectors and techniques

Hereditary diseases in ophthalmology

RECOMMENDED READING/BIBLIOGRAPHY

Reading items will be suggested or delivered by the teacher

TEACHERS AND EXAM BOARD

Exam Board

FEDERICA BARBIERI (President)

LUCA BAGNASCO

MAURO COSTAGLI

MICHELA SACCHEGGIANI

CARLO ALBERTO CUTOLO (Exam Board Member of Integrated Course)

LESSONS

LESSONS START

March

Class schedule

The timetable for this course is available here: Portale EasyAcademy

EXAMS

EXAM DESCRIPTION

Oral exam.

Registration for the exam is required: https://servizionline.unige.it/studenti/esami/

ASSESSMENT METHODS

The exam interview will focus on the topics covered in class: the student will have to demonstrate that he has understood the basic of biomolecular mechanisms and be able to expose what he has learned with awareness

Exam schedule