OVERVIEW

The course of clinical pathology II, III and immunohematology concerns the study of markers of various types of diseases, the study of tests useful for transfusions and organ transplants and the conservation of blood components

AIMS AND CONTENT

LEARNING OUTCOMES

Acquire fundamental, basic and specialized notions on: the main metabolic pathways - regulation mechanisms of carbohydrate, lipid and protein metabolism; structure and function of proteins; enzymology intermediate carbohydrate, lipid and nitrogen metabolism mechanism of action of hormones acid/base balance function markers and of injury. Acquire clinical information on: alterations of the carbohydrate, lipid and nitrogen compounds structure - clinical significance of the parameters of liver and kidney function. Know Acquire the main notions on markers of inflammatory pathology and plasma proteins, markers of cell damage and tumor markers; diagnostics of diabetes and renal and hepatic function. Salt and water balance and acid base. Acquire the theoretical foundations underlying organ and hematopoietic stem cell transplants and autoimmune diseases, with particular reference to compatibility tests and diagnosis and prognosis of autoimmune diseases. Acquire basic notions of immunology and genetics of the major ABO and Rh blood group systems; transfusion compatibility tests; platelet and leukocyte antigens; use of direct and indirect Coombs tests; management and treatment of blood bags in immunohematology. Describe the organization of the transfusion service and blood bank; recognize and list the competences of the TSLB in these structures; distinguish and explain the processing and production procedures of level I and II blood components; list, compare and differentiate the characteristics of blood components; list and describe the biological validation systems of blood components and the tests necessary to ensure the production of safe and effective blood components.

AIMS AND LEARNING OUTCOMES

The course will provide students with the knowledge to understand the meaning of the variances of various groups of disease markers, their clinical correlations and the appropriateness of the prescription. Furthermore, students will be provided with the notions necessary to understand the functioning of organ compatibility and the tests that are carried out to evaluate it. Finally, the course will provide students with the knowledge necessary to understand the functioning of the tests that are used in transfusion centers, both for transfusions and in other clinical conditions in which these tests can be used.

PREREQUISITES

Basic knowledge in biology, anatomy, physiology, biochemistry, general pathology and pathophysiology

TEACHING METHODS

The lessons are held frontally and interactions with students will be sought as much as possible. In consideration of the health situation in our country, the lessons can be delivered online, possibly via live streaming.

Students with documented Specific Learning Disorders (SLD), or with any special needs, shall reach out to the Lecturer(s) and to the dedicated SLD Representative in the Department before class begins, in order to arrange the specific teaching methods and ensure proper achievement of the learning aims and outcomes.

SYLLABUS/CONTENT

See the programs of the individual disciplines included into this integrated course

RECOMMENDED READING/BIBLIOGRAPHY

See the indications for each discipline included into this integrated course

TEACHERS AND EXAM BOARD

Exam Board

ANNA LISA FURFARO (President)

MARIA LIBERA TROTTA (President)

GIANLUCA UBEZIO (President)

NICOLA TRAVERSO (President and Coordinator of Integrated Course)

LESSONS

LESSONS START

II semester of each academic years, according to the information given by the didactic secretery

Class schedule

CLINICAL PATHOLOGY AND IMMUNOHEMATOLOGY I

EXAMS

EXAM DESCRIPTION

The exam will take place through an interview with the student to assess the student's knowledge and the ability to link the learned notions.
In consideration of the health situation in our country, the exams may be conducted remotely.

During the exam, the rules regarding the assessment method of DSA certified students or students with other educational needs indicated by the university will be respected. (e.g.: additional time in the case of written exams, use of concept maps to be viewed for approval by the teachers at least one week before the exam date).

ASSESSMENT METHODS

See the indications for the individual disciplines included into this integrated course.

The tests of the individual disciplines must all be sufficient for the exam to be passed.

During the exam, the rules regarding the assessment method of DSA certified students or students with other educational needs indicated by the university will be respected. (e.g.: additional time in the case of written exams, use of concept maps to be viewed for approval by the teachers at least one week before the exam date).