OVERVIEW

The Clinical Pathology 2 course concerns the study of the meaning of some types of clinical disease markers measured in clinical analysis laboratories

AIMS AND CONTENT

LEARNING OUTCOMES

The educational objective of the course is to provide the student with the fundamental elements on the meaning of some classes of disease markers measurable in the clinical analysis laboratory, with laboratory and clinical correlations

AIMS AND LEARNING OUTCOMES

Provide the student with the knowledge necessary for the meaning of some classes of disease markers (in particular markers of inflammation, cell damage, neoplasm, kidney and liver function and endocrine and metabolic functions) measurable in the laboratory of clinical analyses.
The student must acquire the ability to describe the meaning of the test, remember the reference levels, understand the meaning of values ​​above or below the reference values, know the situations in which a specific test is indicated.

PREREQUISITES

Basic knowledge of biology, histology, anatomy, physiology, biochemistry, general pathology and pathophysiology are prerequisites of the course.

TEACHING METHODS

The lessons are held frontally and interactions with students will be sought as much as possible. In consideration of the health situation in our country, the lessons can be delivered online, possibly via live streaming.

Students with documented Specific Learning Disorders (SLD), or with any special needs, shall reach out to the Lecturer(s) and to the dedicated SLD Representative in the Department before class begins, in order to arrange the specific teaching methods and ensure proper achievement of the learning aims and outcomes.

SYLLABUS/CONTENT

Markers of inflammation, significance of the dosage of plasma proteins, evaluation of the leukocyte formula. Monoclonal Gammapathy. Cell damage markers, enzymatic and non-enzymatic, with clinical correlations. Renal function markers: renal clearance concept, significance of creatinine and plasma urea; estimate of VFG with formulas. Bilirubin: van den Berg test, direct and indirect bilirubin, conjugated and unconjugated bilirubin; clinical correlations. Tumor markers: correct use and correlations with tumor sites; meanings of liquid biopsy and research of circulating tumor DNA. Lipid and carbohydrate metabolism markers. Endocrine function markers. Urinalysis.

RECOMMENDED READING/BIBLIOGRAPHY

Lecture notes on Aulaweb covering all the topics of the program will be provided to students; support books (NOT mandatory): Widmann: Clinical interpretation of laboratory tests, McGrow Hill; M. Ciaccio, G. Lippi: Biochimica Clinica e Medicina di Laboratorio, Edises

TEACHERS AND EXAM BOARD

Exam Board

ANNA LISA FURFARO (President)

MARIA LIBERA TROTTA (President)

GIANLUCA UBEZIO (President)

NICOLA TRAVERSO (President and Coordinator of Integrated Course)

LESSONS

LESSONS START

second semester of the academic year of reference (indicatively beginning of March)

Class schedule

CLINICAL PATHOLOGY

EXAMS

EXAM DESCRIPTION

The exam will take place through an interview with the student to assess the student's knowledge and the ability to link the learned notions.
In consideration of the health situation in our country, the exams may be conducted remotely.

During the exam, the rules regarding the assessment method of DSA certified students or students with other educational needs indicated by the university will be respected. (e.g.: additional time in the case of written exams, use of concept maps to be viewed for approval by the teachers at least one week before the exam date).

ASSESSMENT METHODS

The student will be examined on the contents of at least two chapters covered in the lessons, with questions aimed at assessing his learning and his ability to make connections between the topics. The knowledge and definition of the basic elements of the subject must be known for the exam to be considered sufficient. The ability to critically interpret the value of the analytes on which the examination will focus will be assessed.

During the exam, the rules regarding the assessment method of DSA certified students or students with other educational needs indicated by the university will be respected. (e.g.: additional time in the case of written exams, use of concept maps to be viewed for approval by the teachers at least one week before the exam date).

Exam schedule