CODE 86839 ACADEMIC YEAR 2024/2025 CREDITS 2 cfu anno 4 CHIMICA E TECNOLOGIA FARMACEUTICHE 8451 (LM-13) - GENOVA 2 cfu anno 3 CHIMICA E TECNOLOGIA FARMACEUTICHE 8451 (LM-13) - GENOVA 2 cfu anno 4 FARMACIA 8452 (LM-13) - GENOVA 2 cfu anno 5 FARMACIA 8452 (LM-13) - GENOVA SCIENTIFIC DISCIPLINARY SECTOR CHIM/08 LANGUAGE Italian TEACHING LOCATION GENOVA SEMESTER 2° Semester MODULES Questo insegnamento è un modulo di: OPTIONAL SUBJECTS TEACHING MATERIALS AULAWEB OVERVIEW The use of radiopharmaceuticals is constantly increasing in diagnostic and therapeutic fields. Metabolic radiotherapy is widely used in the treatment of many tumors and the conjugation of specific radionuclides with proteins, particularly with monoclonal antibodies, allows the implementation of specific therapies. Therefore, basic knowledge of this particular area of pharmaceutical chemistry is of paramount importance for students who will become part of the scientific community. AIMS AND CONTENT LEARNING OUTCOMES - provide the student with the basic notions on the activity and use of the most common radiopharmaceuticals, both in the diagnostic and therapeutic fields. - show the student the figure of the radio-pharmacist. AIMS AND LEARNING OUTCOMES Attendance to classes and individual study will allow the student to: - know the topics covered during the teaching; - acquire the ability to apply the acquired knowledge to problems similar to those described; - acquire an adequate scientific language and the ability to connect the various topics covered in the classes or the topics of the course and topics covered in previous teachings. TEACHING METHODS Frontal lessons Any Student with documented Specific Learning Disorders (SLD), or with any special needs, shall reach out to the Lecturer(s) and to the dedicated SLD Representative in the Department ( Prof. Luca Raiteri, Luca.Raiteri@unige.it ) before class begins, in order to liaise and arrange the specific learning methods and ensure proper achievement of the learning aims and outcomes. VERY IMPORTANT: any request for compensatory tools and adaptations in the exam MUST be done within 10 working days before the date of the exam according to the instructions that can be found at https://unige.it/disabilita-dsa/comunicazioni SYLLABUS/CONTENT Definition of radiopharmaceuticals. Radionuclides. Interactions of radiation with matter. Use of radiopharmaceuticals in the diagnostic field. Scintigraphy and PET (positron emission tomography). Production of some radionuclides and radiopharmaceuticals. Therapeutic use of radiopharmaceuticals: metabolic radiotherapy. RECOMMENDED READING/BIBLIOGRAPHY Slides of lessons TEACHERS AND EXAM BOARD FRANCESCA MICHELA MUSUMECI Ricevimento: From Monday to Friday, by email appointment. Exam Board BRUNO TASSO (President) ELEONORA RUSSO (President Substitute) LESSONS Class schedule The timetable for this course is available here: Portale EasyAcademy EXAMS EXAM DESCRIPTION The exam consists of an oral test lasting between 20 and 30 minutes. Students will be required to present part of the topics covered in class. Additionally, it is possible to present a brief in-depth analysis on one of the aspects of radiopharmaceuticals that has sparked the most interest. ASSESSMENT METHODS From the oral interview, the teacher will assess that the student has acquired: 1) knowledge of the topics; 2) competence, i.e., the ability to apply the knowledge acquired to real problems; 3) ability to express concepts clearly with correct terminology and link the various topics covered in the classes or previous courses.