CODE 68475 ACADEMIC YEAR 2025/2026 CREDITS 6 cfu anno 2 TECNICHE DI LABORATORIO BIOMEDICO 9293 (L/SNT3) - GENOVA LANGUAGE Italian TEACHING LOCATION GENOVA PREREQUISITES Propedeuticità in ingresso Per sostenere l'esame di questo insegnamento è necessario aver sostenuto i seguenti esami: BIOMEDICAL LABORATORY TECHNIQUES 9293 (coorte 2024/2025) ANATOMY-HISTOLOGY 65456 2024 PHYSIOLOGY AND BIOCHEMISTRY 66899 2024 PRACTICAL-CLINICAL INTERNSHIP - 1ST YEAR 87016 2024 Propedeuticità in uscita Questo insegnamento è propedeutico per gli insegnamenti: BIOMEDICAL LABORATORY TECHNIQUES 9293 (coorte 2024/2025) APPLIED MEDICAL SCIENCE AND CHROMATOGRAPHIC TECHNIQUES 73159 MODULES Questo insegnamento è composto da: CLINICAL BIOCHEMISTRY HUMAN BIOCHEMISTRY TECHNIQUES OF CLINICAL CHEMISTRY TEACHING MATERIALS AULAWEB OVERVIEW The course aims to develop skills in the field of Clinical Biochemistry and applicable Clinical Chemistry Techniques. AIMS AND CONTENT LEARNING OUTCOMES Acquire fundamental, basic and specialist knowledge on: the main metabolic pathways - mechanisms regulating the metabolism of carbohydrates, lipids and proteins; structure and function of proteins; enzymology intermediate carbohydrate, lipid and nitrogen metabolism mechanism of action of acid/base balance hormones function markers and injury. Acquire clinical information on: alterations in glucose, lipid and nitrogenous compounds - clinical significance of liver and kidney function parameters. Methods of determination of electrophoretic laboratory techniques of serum proteins and urine, giving evidence of the interpretation of the graphs in the main methods; serum and urinary immunofixation with interpretation of results Know laboratory techniques of electrophoretic techniques of serum proteins and urine; Production of radioactive precursors (radioisotopes 18F -11C - 13N) through the use of a circular particle accelerator (cyclotron); preparation of the radiopharmaceutical preparation for clinical purposes, execution of quality controls for the release of the radiopharmaceutical (injectability for the execution of PET imaging diagnostics). Environmental validation aspects for the processing of radiopharmaceuticals in compliance with regulations (Mediafill test and microbiological validations); The Immunometry Techniques course aims to describe the main technical methods used to carry out immunometry tests both with manual methodology and with automatic instruments. The dilution techniques most used in the analysis laboratory are also illustrated PREREQUISITES Nobody TEACHERS AND EXAM BOARD MARIO PASSALACQUA Ricevimento: Dr. Mario Passalacqua, Viale Benedetto Xv,1 16132 Genova Tel 010-3538128 e-mail: Mario.Passalacqua@unige.it MAURIZIO BRUSCHI Ricevimento: On appointment , Prof. Maurizio Bruschi, IRCCS Istituto Giannina Gaslini. Laboratorio di Nefrologia Molecolare (Padiglione 12, fondi) Via Gerolamo Gaslini, 5 – 16147 Genova (GE) E-mail: maurizio.bruschi@unige.it MADDALENA MASTROGIACOMO DANIELA FENOGLIO Ricevimento: The interview with the teacher can be requested by mail or by telephone daniela.fenoglio@unige.it - telephone 010 / 3533027-3029 Study Dr. Daniela Fenoglio, at the Direzione of the Center of Excellence for Biomedical Research (CEBR) - Viale Benedetto XV, 7-16132 Genoa ELISABETTA FRATERNALE Ricevimento: U.O.C Laboratorio di Analisi IRCCS Istituto Giannina Gaslini5, 16147 Genova Tel: 01056362834 E-mail elisabettafraternale@gaslini.org EXAMS EXAM DESCRIPTION See the examination methods of the individual disciplines pertaining to this integrated course. ASSESSMENT METHODS See the methods of accreditation of the single disciplines pertaining to this integrated course.