CODE 104072 ACADEMIC YEAR 2022/2023 CREDITS 3 cfu anno 2 SCIENZA E INGEGNERIA DEI MATERIALI 9017 (LM-53) - GENOVA 3 cfu anno 1 SCIENZA E TECNOLOGIA DEI MATERIALI 11430 (LM SC.MAT.) - GENOVA SCIENTIFIC DISCIPLINARY SECTOR MAT/08 TEACHING LOCATION GENOVA SEMESTER 1° Semester TEACHING MATERIALS AULAWEB OVERVIEW This course aims to introduce the basic computational paradigms of data science and technology, with specific focus on the three pillars of Artificial Intelligence for the data world, i.e. numerical simulation, inverse problems theory and machine learning. Then the course will describe some applications in biochemistry, involving pattern recognition methods for image processing in Scanning Tunnelling Microscopy, the mathematical modelling of tracer kinetics in nuclear medicine and the use of Molecular Interaction Maps in oncology. AIMS AND CONTENT LEARNING OUTCOMES The general objective of the course is to provide students with a first overview of the main issues related to modern data science and its cultural background. The course has also two more specific objectives. The first one is to illustrate some computational tools representing the methodological basis for any artificial intelligence approach to data analysis problems. The second one is to describe three applications concerned with the use of data science methods in chemistry and biochemistry: the problem of the automatic recognition and classification of atomic species in Scanning Tunnelling Microscopy; the modelling of glucose metabolism by means of nuclear medicine data; the simulation of the chemical reaction network at the basis of a specific cellular transition in oncogenesis. AIMS AND LEARNING OUTCOMES The general objective of the course is to provide students with a first overview of the main issues related to modern data science and its cultural background. The course has also two more specific objectives. The first one is to illustrate some computational tools representing the methodological basis for any artificial intelligence approach to data analysis problems. The second one is to describe three applications concerned with the use of data science methods in chemistry and biochemistry: the problem of the automatic recognition and classification of atomic species in Scanning Tunnelling Microscopy; the modelling of glucose metabolism by means of nuclear medicine data; the simulation of the chemical reaction network at the basis of a specific cellular transition in oncogenesis. PREREQUISITES Students attending the course should know in advance the basics of Linear Algebra (vectors, matrices and their norms; linear systems; inversion of a matrix; eigenvalues) TEACHING METHODS lectures and computational laboratory activity SYLLABUS/CONTENT The course is characterized by the following three parts: Computational tools: harmonizing competences (8 hours) Basics of numerical analysis (2 hours) Basics of Bayesian theory (3 hours) Basics of regularization theory (3 hours) Artificial Intelligence: the many aspects of data modeling (10 hrs) Numerical Simulation (2 hours) Inverse Problems (4 hours) Machine Learning (4 hours) Applications to chemical and biochemical data (6 hrs) STM imaging (2 hrs) Tracer kinetics (2 hrs) Chemical Reaction Networks (2 hrs) RECOMMENDED READING/BIBLIOGRAPHY no bibliography TEACHERS AND EXAM BOARD MICHELE PIANA Ricevimento: Office hours by appointment via email Exam Board MICHELE PIANA (President) FEDERICO BENVENUTO (President Substitute) LESSONS LESSONS START not known yet Class schedule The timetable for this course is available here: Portale EasyAcademy EXAMS EXAM DESCRIPTION oral ASSESSMENT METHODS questions about the course syllabus
