CODE 55413 ACADEMIC YEAR 2022/2023 CREDITS 10 cfu anno 1 FARMACIA 8452 (LM-13) - GENOVA SCIENTIFIC DISCIPLINARY SECTOR CHIM/03 LANGUAGE Italian TEACHING LOCATION GENOVA SEMESTER 1° Semester PREREQUISITES Propedeuticità in uscita Questo insegnamento è propedeutico per gli insegnamenti: Pharmacy 8452 (coorte 2022/2023) GENERAL PHARMACOLOGY AND TOXICOLOGY 80324 Pharmacy 8452 (coorte 2022/2023) ANALITICAL CLINICAL CHEMISTRY (PART OF I.C.)(PHAR MD) 64550 Pharmacy 8452 (coorte 2022/2023) PHARMACOLOGY AND PHARMACOTERAPY 80327 Pharmacy 8452 (coorte 2022/2023) PHARMACEUTICAL TECHNOLOGY, SOCIOECONOMY AND LAW II (PHAR MD) 67522 Pharmacy 8452 (coorte 2022/2023) ANALITICAL CHEMISTRY AND ANALITICAL CLINICAL CHEMISTRY (I.C.)(PHAR MD) 64551 Pharmacy 8452 (coorte 2022/2023) COSMETIC PRODUCTS 67501 Pharmacy 8452 (coorte 2022/2023) ORGANIC CHEMISTRY 60795 Pharmacy 8452 (coorte 2022/2023) DIETETIC PRODUCTS 64191 Pharmacy 8452 (coorte 2022/2023) PHARMACEUTICAL TECHNOLOGY SOCIOECONOMY AND LAW I (WITH PRACTICE) 67449 Pharmacy 8452 (coorte 2022/2023) ANALYSIS OF DRUGS I (LM FAR) 80318 Pharmacy 8452 (coorte 2022/2023) ANALYSIS OF DRUGS II 80322 Pharmacy 8452 (coorte 2022/2023) GENERAL MEDICINAL CHEMISTRY AND MEDICINAL CHEMISTRY I 80319 Pharmacy 8452 (coorte 2022/2023) BIOCHEMISTRY AND APPLIED BIOCHEMISTRY 80314 Pharmacy 8452 (coorte 2022/2023) MEDICINAL CHEMISTRY AND TOXICOLOGICAL CHEMISTRY 80337 Pharmacy 8452 (coorte 2022/2023) PHARMACOGNOSY AND PHARMACOVIGILANCE 80328 TEACHING MATERIALS AULAWEB OVERVIEW Inorganic and General Chemistry course is a pivotal class for the education and training of Pharmacists as it provides the knowledge required for the following chemistry classes. This class allows to acquire the scientific language and the skills required for the professional practice. AIMS AND CONTENT LEARNING OUTCOMES The fundamentals of chemistry will be aquired (the matter and its atomic structure, chemical bonds, inorganic compounds, nomenclature, states of matter, principles of thermodynamics, solutions, chemical reactions, chemical equilibrium, electrochemistry, the main chemical properties of the most important elements and inorganic compounds). AIMS AND LEARNING OUTCOMES This course aims to provide the ground knowledge of the chemistry required for the next classes. The learning outcomes will be, together with the acquisition of the ground knowledge of chemistry, the ability to use the scientific language, and solve problems by applying the acquired notions to real cases. TEACHING METHODS Class lessons (80 hours) on the whole program (lessons and exercises) . During adverse situations (such as pandemic ot meteo alert), the lessons might be delivered online by following the University guidelines. Further material on the class can be provided online (ex., Aulaweb or Teams). SYLLABUS/CONTENT Introduction to Chemistry. Elements, compounds and mixtures. Solutions and concentration. Rules of chemical nomenclature. Chemical reactions. Stoichiometry. Gas state. The equation of state of ideal gas. Mixtures of gases and Dalton’s law of partial pressure. The real gases and Van der Waals equation. Thermodynamics. Heat of reaction and enthalpy. Enthropy. Gibbs free energy and spontaneous reactions. Atom. Atomic structure. Atomic orbitals. Electrons and orbitals. Periodic table. Chemical bond. Ionic bond. Covalent bound. Electronegativity. Lewis structures. The VSEPR theory. Hybrid orbitals. Intermolecular forces. Liquid state and solid state. Liquids. Solids. Metallic bond. Phase transitions and phase diagrams for single-component systems. Solutions. Solubility. Ideal solution and Raoult’s law. Colligative properties. Electrolytes. Degree of dissociation. Conductivity of electrolyte solutions. Chemical kynetics. Reaction rate. Collision theory. Factors affecting the rate of reactions. Kinetic equation. Catalysis. Chemical equilibrium. Law of mass action. Equilibrium constant. Le Chatelier’s principle. Homogeneous and heterogeneous equilibrium. Acids and bases. Theories of: Arrhenius, Brønsted-Lowry and Lewis. Strength of acids and bases. Acidity of aqueous solutions: pH. pH indicators. Hydrolysis. Buffer solutions. Solubility equilibrium. Complexes. Electrochemistry. Electrodes and galvanic cells. Reduction potentials and Nernst equation. Electrolysis. Faraday’s laws. Accumulators. Inorganic chemistry. Hydrogen. Main characteristics of the elements of 1, 2, 13, 14, 15, 16, 17, 18 Groups and their most representative compounds. Characteristics of the elements of d-block and representative compounds. RECOMMENDED READING/BIBLIOGRAPHY The recommended books are: - Peter Atkins, Loretta Jones, “CHIMICA GENERALE”, Ed. Zanichelli. - Peter Atkins, Loretta Jones, Leroy Laverman, “PRINCIPI DI CHIMICA” (4th edition), Zanichelli Other books of General and Inorganic Chemistry at university level can be used, e.g.: - Kotz, Treichel, Townsend, Treichel “CHIMICA”, VII ed., Ed. Edises - Brown, Lemay, Bursten, Murphy, Woodward, “FONDAMENTI DI CHIMICA”, Ed. Edises - Casarin, Casella, D'Agostino, Filippi, Grandinetti, Purrello, Re, Speranza, "CHIMICA GENERALE E INORGANICA" a cura di M. Speranza, Ed. Edi-ermes - Petrucci, Herring, Madura, Bissonnette, “CHIMICA GENERALE. Principi ed applicazioni moderne" (+ complete solutions manual), Ed. Piccin TEACHERS AND EXAM BOARD VALERIO VOLIANI Ricevimento: Students can contact the lecturer to arrange a meeting by email at: valerio.voliani@unige.it Exam Board VALERIO VOLIANI (President) GIULIANA DRAVA MONICA CASALE (Substitute) RICCARDO LEARDI (Substitute) VINCENZO MINGANTI (Substitute) PAOLO OLIVERI (Substitute) PAOLA RIANI (Substitute) LESSONS Class schedule The timetable for this course is available here: Portale EasyAcademy EXAMS EXAM DESCRIPTION The exam consists of two compulsory parts: a written test followed by an oral test. The written test consists in: - a multiple choice test (30 questions, including numerical problems and chemical reactions). The students can view their test and discuss the outcome it with the lecturer. The minimum score to be admitted to the oral exam is 18/30. If the score is LESS THAN 12/30, the student is not ammitted to the following written test if scheduled within the next 20 days. The oral exam is conducted by two professors of the academic staff. It covers the whole program, and can rest for max 30 minutes. During advense events (such as health emergency), the exams can be attended online accordingly to the University guidelines. ASSESSMENT METHODS The exam aims to assess: - the knowledge of the discipline (test) - the acquisition of a correct scientific language (oral exam); - general and specific problem-solving skills (test and oral exam). Exam schedule Data appello Orario Luogo Degree type Note 11/04/2023 11:00 GENOVA Scritto + Orale 19/06/2023 11:00 GENOVA Scritto + Orale 03/07/2023 11:00 GENOVA Scritto + Orale 17/07/2023 11:00 GENOVA Scritto + Orale 06/09/2023 11:00 GENOVA Scritto + Orale 22/01/2024 11:00 GENOVA Scritto + Orale 05/02/2024 11:00 GENOVA Scritto + Orale