Composite materials are very useful in biomedical engineering but their use requires special care. The course focuses on the study of the characteristics of composite materials and their design methodologies. The materials for the construction of exoprostheses as well as those for endoprostheses will be examined. Definition of matrix and reinforcement. Study of the anisotropic aspects of composites. Characteristics and construction of the main long fiber reinforcements (carbon fibers) and particulate(ceramic-based) composite. Interaction and adhesion between reinforcement and matrix, defects and problems inherent to technology and materials. Prepregs and separate component systems. Woven and non woven materials. Fracture of fibers and laminates, scaffolds and hybrid systems. Reinforcement sizing and layering treatments. Ceramic matrix fibers and composites. Manufacturing techniques. The course will be completed by a module on regulatory aspects in designing with innovative materials.