CODE 67377 ACADEMIC YEAR 2025/2026 CREDITS 8 cfu anno 3 MEDICINA E CHIRURGIA 8745 (LM-41) - GENOVA LANGUAGE Italian TEACHING LOCATION GENOVA PREREQUISITES Propedeuticità in ingresso Per sostenere l'esame di questo insegnamento è necessario aver sostenuto i seguenti esami: MEDICINE AND SURGERY 8745 (coorte 2023/2024) GENERAL PHYSIOPATHOLOGY 67362 2023 CLINICAL DIAGNOSIS 67363 2023 ETIOLOGY AND PATHOGENESIS OF DISEASES 72088 2023 Propedeuticità in uscita Questo insegnamento è propedeutico per gli insegnamenti: MEDICINE AND SURGERY 8745 (coorte 2023/2024) MEDICINE 67519 MODULES Questo insegnamento è composto da: PATHOLOGICAL ANATOMY CUTANEOUS AND VENEREAL DISEASES INTERNAL MEDICINE (CLINICAL IMMUNOLOGY) RHEUMATOLOGY TEACHING MATERIALS AULAWEB OVERVIEW The Integrated Course of Dermatology, Clinical Immunology, and Rheumatology aims to address the epidemiology, etiology, pathogenesis, clinical manifestations, differential diagnosis, and therapeutic insights of the main diseases related to these three medical branches. Some lessons will be delivered in a multidisciplinary format, since several conditions share clinical features across the three disciplines. Lectures will cover and explore only a portion of the clinical topics, as a complete discussion of all diseases is not feasible within the allocated teaching hours. However, exam topics will include all diseases within the fields of Dermatology, Clinical Immunology, and Rheumatology. Lectures will be held in-person and will include both the discussion of diseases and the presentation of clinical cases to be discussed interactively. The exam will be oral. AIMS AND CONTENT LEARNING OUTCOMES Cognitive understanding of the main dermatological, immunological, and rheumatological diseases. The student should be able to recognize the pathophysiological bases, morphological alterations, and clinical manifestations of the main diseases and their complications. Additionally, the student should be able to determine a diagnostic process and prognosis. AIMS AND LEARNING OUTCOMES The Integrated Course of Dermatology, Clinical Immunology, and Rheumatology addresses the epidemiology, etiology, pathogenesis, clinical manifestations, differential diagnosis, and therapeutic insights of major diseases in these fields. The student will be able to recognize the pathophysiological bases, morphological changes, and clinical manifestations of the main diseases and their complications and establish a diagnostic pathway and prognosis. PREREQUISITES Knowledge of the basics of immunology, immunoinflammation, and human anatomy TEACHING METHODS Lessons are held in-person, with optional tutorial sessions at the bedside or in outpatient clinics involving clinical case discussions. Students with valid certifications for Specific Learning Disorders (SLD), disabilities, or other educational needs are invited to contact the professor and the school's/department's disability coordinator at the beginning of the course to arrange suitable teaching methods that respect the course objectives while accommodating individual learning styles. SYLLABUS/CONTENT Immunology Topics Approach to patients with allergic or immunological disorders Primary and secondary immunodeficiencies Autoimmunity and autoantibodies Organ-specific autoimmune diseases Allergic diseases (asthma, rhinitis) Urticaria and angioedema Hypersensitivity reactions and anaphylaxis Food, insect sting, and drug allergies Mastocytosis Recommended textbook: Harrison's Principles of Internal Medicine, Libreria Universo, 2021. Rheumatology Topics Approach to patients with rheumatologic diseases: physical examination, rheumatologic semiotics, and inflammatory markers Rheumatoid arthritis Ankylosing spondylitis and spondyloarthritis, Psoriatic arthritis, Reactive arthritis, Lyme disease, Acute rheumatic fever, Enteropathic arthritis Septic arthritis Primary and secondary Raynaud's phenomenon Connective tissue diseases: (Systemic lupus erythematosus, Systemic sclerosis, Mixed connective tissue disease, Overlap syndromes, Dermatomyositis and Polymyositis) Sjögren’s syndrome Vasculitis Crystal-induced and metabolic arthropathies Osteoarthritis Soft tissue and extra-articular diseases Fibromyalgia Polymyalgia rheumatica Osteoporosis, osteomalacia, rickets, bone and extra-bone roles of vitamin D Paget’s disease of bone Hereditary connective tissue diseases Nerve compression syndromes Synovial fluid examination Imaging techniques in rheumatology Recommended textbook: UNIREUMA. Rheumatology for Students and General Practitioners, Ed. Gnocchi 2021. Dermatology Topics Primary skin lesions Eczema Psoriasis Lichen planus Urticaria Drug-induced skin reactions Photodermatitis Cutaneous mycoses Parasitic infestations and scabies Protozoan diseases Bacterial skin diseases Syphilis Dermatomyositis Lupus Scleroderma/Morphea Autoimmune bullous diseases Actinic keratosis Basal and squamous cell carcinomas Melanoma Reference textbook: Manual of Medical and Surgical Dermatology, 6th edition, ISBN 8838639930 - 9788838639937, by Tullio Cainelli, Alberto Giannetti, Alfredo Rebora. © 2016 | Publication Date: June 9, 2016. RECOMMENDED READING/BIBLIOGRAPHY Harrison's Principles of Internal Medicine, McGra-Hill Education 2022. UNIREUMA. Rheumatology for Students and General Practitioners, Ed. Gnocchi 2021. Manual of Medical and Surgical Dermatology, 6th edition, ISBN 8838639930 - 9788838639937, by Tullio Cainelli, Alberto Giannetti, Alfredo Rebora. © 2016 | Publication Date: June 9, 2016. TEACHERS AND EXAM BOARD EMANUELE CLAUDIO COZZANI DANIELA FENOGLIO Ricevimento: The interview with the teacher can be requested by mail or by telephone daniela.fenoglio@unige.it - telephone 010 / 3533027-3029 Study Dr. Daniela Fenoglio, at the Direzione of the Center of Excellence for Biomedical Research (CEBR) - Padiglione 3, first floor-16132 Genoa GILBERTO FILACI Ricevimento: By appointment via email: gfilaci@unige.it RAFFAELE DE PALMA Ricevimento: By appointment via email:raffaele.depalma@unige.it GIAMPAOLA PESCE GIUSEPPE MURDACA Ricevimento: By appointment via email: giuseppe.murdaca@unige.it SABRINA PAOLINO Ricevimento: By appointment via email:sabrina.paolino@unige.it CARMEN PIZZORNI Ricevimento: The teacher receives by appointment: 010/3538669 0105557691 carmen.pizzorni@unige.it ALBERTO SULLI Ricevimento: By appointment via email:alberto.sulli@unige.it EMANUELE GOTELLI Ricevimento: By appointment via email:emanuele.gotelli@unige.it LUCA MASTRACCI Ricevimento: Please contact for appointment by mail (luca.mastracci@unige.it). CARLO PESCE Ricevimento: By appointment via email:carlomario.pesce@unige.it Mondays 10AM-12AM LESSONS LESSONS START See the academic calendar on the EasyAcademy portal Class schedule The timetable for this course is available here: Portale EasyAcademy EXAMS EXAM DESCRIPTION The final exam is a single oral exam covering the entire integrated course. It consists of questions on the topics covered in the disciplines included into the integrated teaching. The purpose is to assess the student’s understanding of the course/module objectives. The final grade is expressed out of 30, with honors possible. The exam is considered passed if the grade is at least 18/30. ASSESSMENT METHODS Student learning is assessed solely through the final exam, which aims to verify the achievement of the expected learning outcomes.