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BIOCHEMISTRY

CODE 65467
ACADEMIC YEAR 2022/2023
CREDITS
  • 1 cfu during the 1st year of 11477 ASSISTENZA SANITARIA (L/SNT4) - GENOVA
  • 1 cfu during the 1st year of 9298 TECNICHE DELLA PREVENZIONE NELL'AMBIENTE E NEI LUOGH(L/SNT4) - GENOVA
  • 1 cfu during the 1st year of 9286 TECNICA DELLA RIABILITAZIONE PSICHIATRICA(L/SNT2) - GENOVA
  • 1 cfu during the 1st year of 9294 TECNICHE DI RADIOLOGIA MEDICA, PER IMMAGINI E RADIOT(L/SNT3) - GENOVA
  • 1 cfu during the 1st year of 9281 FISIOTERAPIA(L/SNT2) - GE SAN MARTINO
  • 1 cfu during the 1st year of 9282 LOGOPEDIA(L/SNT2) - GENOVA
  • 1 cfu during the 1st year of 9287 TERAPIA DELLA NEURO E PSICOMOTRICITA' DELL'ETA' EVOL(L/SNT2) - GENOVA
  • 1 cfu during the 1st year of 9283 ORTOTTICA ED ASSISTENZA OFTALMOLOGICA(L/SNT2) - GENOVA
  • 1 cfu during the 1st year of 9281 FISIOTERAPIA(L/SNT2) - CHIAVARI
  • 1 cfu during the 1st year of 9291 TECN.FISIOPATOL.CARDIOCIRCOLAT.E E PERFUS.CARDIOVASC(L/SNT3) - GENOVA
  • 1 cfu during the 1st year of 9297 TECNICHE ORTOPEDICHE(L/SNT3) - GENOVA
  • 1 cfu during the 1st year of 9284 PODOLOGIA(L/SNT2) - GENOVA
  • 1 cfu during the 1st year of 9281 FISIOTERAPIA(L/SNT2) - PIETRA LIGURE
  • 1 cfu during the 1st year of 9281 FISIOTERAPIA(L/SNT2) - LA SPEZIA
  • 1 cfu during the 1st year of 9289 IGIENE DENTALE(L/SNT3) - GENOVA
    		•
    SCIENTIFIC DISCIPLINARY SECTOR BIO/10
    LANGUAGE Italian
    TEACHING LOCATION
  • GENOVA
  • GE SAN MARTINO
  • CHIAVARI
  • PIETRA LIGURE
  • LA SPEZIA
    		•
    SEMESTER 2° Semester
    SECTIONING This unit is divided into 2 sections:
    MODULES This unit is a module of:
    TEACHING MATERIALS AULAWEB

    OVERVIEW

    The course consist of two modules: Propedeutical Biochemistry and Biochemistry, and is divided into two parts: a part of lessons in presence and one part, as support of the first, consisting of online classes.

    AIMS AND CONTENT

    LEARNING OUTCOMES

    The first part of the course aims to provide the basis of general and organic chemistry to address Biochemistry,  the second part of the course. The aim of this second part is both the acquisition of knowledge about the structure and function of proteins and enzymes proteins as the main pathways of carbohydrate, fat, and protein catabolism.

    TEACHING METHODS

    Lectures in presence,  supported / supplemented by recorded lectures that the students can access online through the platform AulaWeb

    SYLLABUS/CONTENT

    PROPEDEUTICAL BIOCHEMISTRY solutions. Properties and  units of measure: molarity, normality,% w / w% w / v. osmotic pressure. The chemical reactions. chemical balance. chemical kinetics. Reaction speed. Catalysis and enzymatic catalysis, Km. Thermodynamics. Concepts of enthalpy and entropy. Spontaneity of reactions, free energy. Ionization of water. pH. Acidity and alkalinity. Strong and weak acids and bases,  hydrolysis, buffers. The chemistry of carbon, the carbon valence. The functional groups. Alcohols and thiols. Redox reactions. Oxidation of alcohols and thiols. Aldehydes and ketones. Hemiacetals. Amines. Carboxylic acid. Amides, esters and anhydrides. Fatty acids. Triglycerides. Phospholipids. Biomolecules and their functional groups. Carbohydrates: Monosaccharides: glucose, fructose, ribose and deoxyribose, disaccharides: sucrose, and polysaccharides, cellulose, glycogen. Amino acids. Peptides and proteins. The peptide bond. protein structure.

    Biochemistry Myoglobin.  Hemoglobin. Enzymes: structure and function. Catabolism and anabolism: general concepts of the intermediate metabolism. Glycolysis, gluconeogenesis and glucose:  regulation. Lactate cycle. Krebs cycle. Strategies for ATP synthesis. Synthesis and degradation of glycogen. Oxidation of fatty acids. Chetonic bodies. Amino acids catabolism: urea cycle.

    RECOMMENDED READING/BIBLIOGRAPHY

    Catani, Savini, Guerrieri, Avigliano “Appunti di Biochimica per le lauree triennali” Editore: Piccin
    Stefani, Taddei “Chimica biochimica e biologia applicata” Editore: Zanichelli

    TEACHERS AND EXAM BOARD

    Exam Board

    PIETRO BALDELLI (President)

    GIANLUCA DAMONTE (President)

    LAURA AVANZINO

    ANNA FASSIO

    CATERINA MICHETTI

    ENRICO MILLO

    MARIO PASSALACQUA

    LAURA STURLA

    PIERLUIGI VALENTE

    LESSONS

    LESSONS START

    II SEMESTER – STARTING FROM MARCH 2017

    Class schedule

    All class schedules are posted on the EasyAcademy portal.

    EXAMS

    EXAM DESCRIPTION

    Oral examination

    ASSESSMENT METHODS

    For the units with video lessons,  self-assessment tests, which are designed to stimulate students in learning, are provided.  Self-assessment tests are useful also to verify the correct understanding, facilitating the preparation of the final exam, done in the presence.