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HUMAN PHYSIOLOGY

CODE 65464
ACADEMIC YEAR 2022/2023
CREDITS
  • 2 cfu during the 1st year of 11477 ASSISTENZA SANITARIA (L/SNT4) - GENOVA
  • 2 cfu during the 1st year of 9298 TECNICHE DELLA PREVENZIONE NELL'AMBIENTE E NEI LUOGH(L/SNT4) - GENOVA
  • 2 cfu during the 1st year of 9286 TECNICA DELLA RIABILITAZIONE PSICHIATRICA(L/SNT2) - GENOVA
  • 2 cfu during the 1st year of 9288 DIETISTICA(L/SNT3) - GENOVA
  • 2 cfu during the 1st year of 9294 TECNICHE DI RADIOLOGIA MEDICA, PER IMMAGINI E RADIOT(L/SNT3) - GENOVA
  • 2 cfu during the 1st year of 9281 FISIOTERAPIA(L/SNT2) - GE SAN MARTINO
  • 2 cfu during the 1st year of 9282 LOGOPEDIA(L/SNT2) - GENOVA
  • 2 cfu during the 1st year of 9293 TECNICHE DI LABORATORIO BIOMEDICO(L/SNT3) - GENOVA
  • 2 cfu during the 1st year of 9287 TERAPIA DELLA NEURO E PSICOMOTRICITA' DELL'ETA' EVOL(L/SNT2) - GENOVA
  • 2 cfu during the 1st year of 9283 ORTOTTICA ED ASSISTENZA OFTALMOLOGICA(L/SNT2) - GENOVA
  • 2 cfu during the 1st year of 9281 FISIOTERAPIA(L/SNT2) - CHIAVARI
  • 2 cfu during the 1st year of 9291 TECN.FISIOPATOL.CARDIOCIRCOLAT.E E PERFUS.CARDIOVASC(L/SNT3) - GENOVA
  • 2 cfu during the 1st year of 9297 TECNICHE ORTOPEDICHE(L/SNT3) - GENOVA
  • 2 cfu during the 1st year of 9284 PODOLOGIA(L/SNT2) - GENOVA
  • 2 cfu during the 1st year of 9281 FISIOTERAPIA(L/SNT2) - PIETRA LIGURE
  • 2 cfu during the 1st year of 9281 FISIOTERAPIA(L/SNT2) - LA SPEZIA
  • 2 cfu during the 1st year of 9289 IGIENE DENTALE(L/SNT3) - GENOVA
  • SCIENTIFIC DISCIPLINARY SECTOR BIO/09
    LANGUAGE Italian
    TEACHING LOCATION
  • GENOVA
  • GE SAN MARTINO
  • CHIAVARI
  • PIETRA LIGURE
  • LA SPEZIA
  • SEMESTER 2° Semester
    MODULES This unit is a module of:
    TEACHING MATERIALS AULAWEB

    OVERVIEW

    This course aims to supply an overview of General Physiology, from cellular to integrative level

    AIMS AND CONTENT

    AIMS AND LEARNING OUTCOMES

    Knowledge & understanding

    At the end of the course, the student will have to know:

             the general principles of cellular physiology

             organ and system physiology, both comparative and human

             the mechanisms of internal homeostasis regulation

     Applying knowledge & understanding

     

    At the end of the course the student will be able to:

             recognize and understand physiological parameters of the different cellular types and organs and the outcomes of their alteration

             apply the acquired knowledges in the research field, both general and applied, and in the production area

     Making judgements

     At the end of this teaching, the student will be able to:

             interpret experimental data in both cellular and organ physiology

     Communications skills

     At the end of this teaching, the student will be able to:

             utilize properly scientific language, in particular respect to physiological terms

             outline and show in a professional context the main physiological mechanisms

     

    PREREQUISITES

    The student would be familiar with general principles of General and Organic Chemistry, Physics, Biochemistry and Cellular and Tissue Biology.

     

     

    TEACHING METHODS

    Lectures: 20 hours. The lessons will be held in presence. Lectures, interactive simulations, and discussion in presence on the topics of the program.

    SYLLABUS/CONTENT

             General concepts and principles of physiology. Intra- and extracellular fluids composition and adaptations to the external environment. Homeostasis.

             Plasma membrane: energy and materials transports across cell membrane. How charged or uncharged molecules are transported: ionic channels and carriers. Structure and function of membrane transporters. Active and passive mechanisms. Water movements. Osmotic pressure. Transports across epithelia. Cell communication: how chemical messangers work.

             Electric properties of plasma membrane and physiology of neurons. Resting membrane potential. Ionic selectivity of biological membranes. Transient variations of membrane potential, generation of electrical signals and effects on cell functions. Neurons and nervous signals: cell excitation, synapsis and neuronal integration. Signal processing and general principles of neuronal networks: convergence and divergence, inhibitory and excitatory interneurons in feedback/forward pathways. Transmission along the axon.

             Muscle physiology. The skeletal muscle in vertebrates: molecular basis of contraction. Calcium release from sarcoplasmic reticulum and excitation-contraction coupling. Mechanical events in muscle contraction. Muscle contraction regulation in the different types of muscle fibers (skeletal, smooth and cardiac muscle).

             Circulatory system. Structure and functions of the heart and circulatory system in vertebrates. The heart as a pump (electrical and mechanical activities of the heart). Blood vessels and circulation: pressure and velocity of blood, the capillaries and equilibration with interstitial fluid. Regulatory mechanisms and adaptations of the heart and circulatory system.

             Respiratory physiology: general principles, structure and functions of air passages and respiratory surfaces; the effect of environment of respiration and comparative physiology of respiration. Mechanics of respiration and gas exchanges. Gas transport between the lungs and tissues: structure and function of hemoglobin, the transport of carbon dioxide and the blood as a buffer. Regulation of the respiration: neural and chemical control of the breathing, respiratory adjustments during exercise.

             Renal physiology. Functional anatomy of the kidney, glomerular filtration, tubular processes of absorption and secretion, comparative properties of the nephron, water-salts balance.

    RECOMMENDED READING/BIBLIOGRAPHY

     Titolo: Fisiologia umana. Un approccio integrato - Editore: Pearson - Autore: D.U. Silverthorn - ISBN:  9788891909732

    Titolo: Fisiologia Medica - Editore: EDRA - Autore:  Guyton at Hall - ISBN:9788821455414

     

     

     

    TEACHERS AND EXAM BOARD

    Exam Board

    PIETRO BALDELLI

    ANNA FASSIO

    ENRICO MILLO

    MARIO PASSALACQUA

    LESSONS

    LESSONS START

     The lessons will start in the second semester in accordance with the didactic calendar

    Class schedule

    All class schedules are posted on the EasyAcademy portal.

    EXAMS

    EXAM DESCRIPTION

    Oral exam.  The oral exam, lasting about twenty minutes, involve one question of neurophysiology asked by one teachers of the commission. The grade will be mediated with the one of Human Physiology as regards the Physiology course of the Physiology and Biochemistry integrated course.

    ASSESSMENT METHODS

    Oral test aims to verify the basic knowledge presented in the program. Language properties, clarity of presentation, consequentiality of reasoning and analytical capacity are also evaluated.