CODE 72720 ACADEMIC YEAR 2022/2023 CREDITS 1 cfu anno 1 9281 (L/SNT2) - LA SPEZIA SCIENTIFIC DISCIPLINARY SECTOR BIO/13 LANGUAGE Italian TEACHING LOCATION GENOVA GE SAN MARTINO CHIAVARI PIETRA LIGURE LA SPEZIA SEMESTER 1° Semester MODULES Questo insegnamento è un modulo di: BIOLOGY AND GENETICS TEACHING MATERIALS AULAWEB OVERVIEW This course provides a basic outline of the principles of classical genetics Methods to determine the relative positions of genes in the genome are explained, and various patterns of inheritance are described. The main areas that are covered are: transmission genetics, gene and genome structure, stability and variability mechanisms. The course also provides students with the skills to solve simple genetic problems .This is carried out by using an interactive approach.a AIMS AND CONTENT AIMS AND LEARNING OUTCOMES This class will help students to develop knowledge, understanding and a strong foundation in genetics basics. Aim of this course is to provide students with knowledge of the basic principles of Genetics as well as the ability to analyze basicl problems regarding the same topics so to develop their analytic skills. By attending class and then by studying on their own what discussed during lessons, students will acquire knowledge of: - general mechanisms of inheritance, with particular attention to human heredity - fundamentals of molecular genetics mechanisms that underlie monogenic inheritance models . -basic features of the process and the molecular basis of mutations -potential medical applications using simulation exercises. TEACHING METHODS Students are required to attend class for at least 75% of the scheduled lessons. Class will be managed as frontal lectures with Power Point notes. Basics in genetics will be addressed during class by means of active discussion engaged by the Lecturer via examples and specific exercise with the Lecturer assistance in solving simple genetic problems Students can take advantage of online material (lectures power point notes) available on the AulaWeb website; Lecturer can be reached via email to arrange specific 1-to-1 meeting for further assistance/explanation as needed. SYLLABUS/CONTENT Mitosis versus Meiosis Basic principles of inheritance: applications of Mendel's principles to eukaryotes followed by an introduction to humans (notions of features of autosomal dominant and recessive inheritance) Sex-chromosomes and the chromosomal theory of inheritance. Sex-linked traits Extensions of Mendel's classic genetics: allelic variations, gene-gene interactions, gene-environment interactions Linked genes: recombination and gene mapping in eukaryotes. Basic features of mutations: molecular basis of mutation and different phenotypic effects. Chemical and physical mutagens. RECOMMENDED READING/BIBLIOGRAPHY Power point notes of class lectures are available for students to be downloaded from AulaWeb (https://www.aulaweb.unige.it). Files are strictly for personal use only; files must not be shared on social media, posted on any internet website or put on any sharing platform; files must not be printed out for sale or photocopied. Other basic genetics textbooks can be also used, providing they are intended for University Master Degree courses. TEACHERS AND EXAM BOARD SVEVA BOLLINI Ricevimento: Prof. Sveva Bollini office hours for students are normally set by previous appointment requested by email. The office address is: Biology Section, Dept. Experimental Medicine; entrance: Via Pastore 3 or C.so Europa 30, second floor or Torre C3, c/o CBA, Cellular Oncology Lab, L. go R. Benzi 10, 16132 Genova. The lecturer's e-mail address and phone number are the following: sveva.bollini@unige.it; 0105558394. If necessary appointments may also take place on-line, depending on previous agreements between students and lecturer. LESSONS Class schedule L'orario di tutti gli insegnamenti è consultabile all'indirizzo EasyAcademy. EXAMS EXAM DESCRIPTION The exam assessment will be performed by written multiple choice test. The assessment of the integrated course is made up of a single written exam for the 4 sub-sections(10 multiple choice questions per each module: Biology, General Genetics, Medical Genetics and Microbiology). In order to pass the class athe student has to reach a mark of at least 24/40 (18/30). The total amount of time allowed for the exam is 60 minutes. Students enrolled in other universities or other degree courses who are only required to sit for some of the sub-sections must achieve an average mark of at least 6, 12 or 18, depending on the number of modules ASSESSMENT METHODS Students are assessed by a final exam alone which aims to ensure that they have actually reached the required level of knowledge. In order to pass the class, students must reach a mark of at least 18/30. Exam schedule Data Ora Luogo Degree type Note 09/01/2023 09:30 GENOVA Scritto 9/1/2023 Aula Teledidattica – Polo Biomedico 14/2/2023 Aula Infolinguistica – Polo Alberti 16/6/2023 Aula Infolinguistica – Polo Alberti 20/7/2023 Aula Infolinguistica – Polo Alberti 12/9/2023 Aula Teledidattica – Polo Biomedico h 9,30 (presentarsi alle 9 per l’appello) 14/02/2023 09:30 GENOVA Scritto 9/1/2023 Aula Teledidattica – Polo Biomedico 14/2/2023 Aula Infolinguistica – Polo Alberti 16/6/2023 Aula Infolinguistica – Polo Alberti 20/7/2023 Aula Infolinguistica – Polo Alberti 12/9/2023 Aula Teledidattica – Polo Biomedico h 9,30 (presentarsi alle 9 per l’appello) 16/06/2023 09:30 GENOVA Scritto 9/1/2023 Aula Teledidattica – Polo Biomedico 14/2/2023 Aula Infolinguistica – Polo Alberti 16/6/2023 Aula Infolinguistica – Polo Alberti 20/7/2023 Aula Infolinguistica – Polo Alberti 12/9/2023 Aula Teledidattica – Polo Biomedico h 9,30 (presentarsi alle 9 per l’appello) 20/07/2023 09:30 GENOVA Scritto 9/1/2023 Aula Teledidattica – Polo Biomedico 14/2/2023 Aula Infolinguistica – Polo Alberti 16/6/2023 Aula Infolinguistica – Polo Alberti 20/7/2023 Aula Infolinguistica – Polo Alberti 12/9/2023 Aula Teledidattica – Polo Biomedico h 9,30 (presentarsi alle 9 per l’appello) 12/09/2023 09:30 GENOVA Scritto 9/1/2023 Aula Teledidattica – Polo Biomedico 14/2/2023 Aula Infolinguistica – Polo Alberti 16/6/2023 Aula Infolinguistica – Polo Alberti 20/7/2023 Aula Infolinguistica – Polo Alberti 12/9/2023 Aula Teledidattica – Polo Biomedico h 9,30 (presentarsi alle 9 per l’appello) FURTHER INFORMATION All the topics covered in class can be found in the ”aula web” slides. Any other, more in-depth material is mentioned at the end of the lesson and can be found in the “aula web” slides. https://www.aulaweb.unige.it For further explanations, Lecturers are available to arrange one-to-one meetings; students can contact them via e-mail or phone call.
